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A selective CuII complex with 4-fluorophenoxyacetic acid hydrazide and phenanthroline displays DNA-cleaving and pro-apoptotic properties in cancer cells.
Machado PHA, Paixão DA, Lino RC, de Souza TR, de Souza Bontempo NJ, Sousa LM, Van Petten de Vasconcelos Azevedo F, Orsolin PC, Lima PMAP, Martins IC, da Costa Guerra JF, Teixeira SC, Araújo TG, Goulart LR, Morelli S, Guerra W, de Oliveira Júnior RJ. Machado PHA, et al. Among authors: martins ic. Sci Rep. 2021 Dec 27;11(1):24450. doi: 10.1038/s41598-021-03909-1. Sci Rep. 2021. PMID: 34961767 Free PMC article.
A novel peptide-based electrochemical biosensor for breast cancer characterization over a poly 3-(3-aminophenyl) propionic acid matrix.
da Fonseca Alves R, Martins IC, Franco DL, Silva ADG, de Souza Santos P, Goulart LR, Cristina de Paiva Maia Y, Faria Silva AT, Gonçalves Araújo T, Del Pilar Taboada Sotomayor M. da Fonseca Alves R, et al. Among authors: martins ic. Biosens Bioelectron. 2022 Jun 1;205:114081. doi: 10.1016/j.bios.2022.114081. Epub 2022 Feb 21. Biosens Bioelectron. 2022. PMID: 35217253
Copper(II) Complex Containing 4-Fluorophenoxyacetic Acid Hydrazide and 1,10-Phenanthroline: A Prostate Cancer Cell-Selective and Low-Toxic Copper(II) Compound.
Bontempo NJS, Paixão DA, Lima PMAP, Barros DCT, Borges DS, Orsolin PC, Martins IC, Machado PHA, Lino RC, Souza TR, Ramos LMS, Teixeira SC, Siqueira RP, Goulart Filho LR, Guerra W, Oliveira Júnior RJ, Araújo TG. Bontempo NJS, et al. Among authors: martins ic. Molecules. 2022 Oct 20;27(20):7097. doi: 10.3390/molecules27207097. Molecules. 2022. PMID: 36296690 Free PMC article.
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz SH, Alemãn-Serrano N, Atalaia-Barbacena H, Ribeiro-Rodrigues L, Ramalho RM, Pinto R, Miranda HV, Tanqueiro SR, de Almeida-Borlido C, Ramalho MJ, Miranda-Lourenço C, Belo RF, Ferreira CB, Neves V, Rombo DM, Viais R, Umemori J, Martins IC, Jerónimo-Santos A, Caetano A, Manso N, Mäkinen P, Marttinen M, Takalo M, Bremang M, Pike I, Haapasalo A, Loureiro JA, Pereira MC, Santos NC, Outeiro TF, Castanho MARB, Fernandes A, Hiltunen M, Duarte CB, Castrén E, de Mendonça A, Sebastião AM, Rodrigues TM, Diógenes MJ. Fonseca-Gomes J, et al. Among authors: martins ic. Mol Ther. 2025 Jan 8;33(1):421. doi: 10.1016/j.ymthe.2024.12.005. Epub 2024 Dec 12. Mol Ther. 2025. PMID: 39672159 No abstract available.
A small TAT-TrkB peptide prevents BDNF receptor cleavage and restores synaptic physiology in Alzheimer's disease.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz SH, Alemãn-Serrano N, Atalaia-Barbacena H, Ribeiro-Rodrigues L, Ramalho RM, Pinto R, Vicente Miranda H, Tanqueiro SR, de Almeida-Borlido C, Ramalho MJ, Miranda-Lourenço C, Belo RF, Ferreira CB, Neves V, Rombo DM, Viais R, Umemori J, Martins IC, Jerónimo-Santos A, Caetano A, Manso N, Mäkinen P, Marttinen M, Takalo M, Bremang M, Pike I, Haapasalo A, Loureiro JA, Pereira MC, Santos NC, Outeiro TF, Castanho MARB, Fernandes A, Hiltunen M, Duarte CB, Castrén E, de Mendonça A, Sebastião AM, Rodrigues TM, Diógenes MJ. Fonseca-Gomes J, et al. Among authors: martins ic. Mol Ther. 2024 Oct 2;32(10):3372-3401. doi: 10.1016/j.ymthe.2024.08.022. Epub 2024 Aug 27. Mol Ther. 2024. PMID: 39205389 Free article.
71 results