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Structure-Based Design and Biological Evaluation of Novel Caspase-2 Inhibitors Based on the Peptide AcVDVAD-CHO and the Caspase-2-Mediated Tau Cleavage Sequence YKPVD314.
Bresinsky M, Strasser JM, Vallaster B, Liu P, McCue WM, Fuller J, Hubmann A, Singh G, Nelson KM, Cuellar ME, Wilmot CM, Finzel BC, Ashe KH, Walters MA, Pockes S. Bresinsky M, et al. Among authors: singh g. ACS Pharmacol Transl Sci. 2022 Jan 5;5(1):20-40. doi: 10.1021/acsptsci.1c00251. eCollection 2022 Jan 14. ACS Pharmacol Transl Sci. 2022. PMID: 35059567 Free PMC article.
Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy.
Singh G, Liu P, Yao KR, Strasser JM, Hlynialuk C, Leinonen-Wright K, Teravskis PJ, Choquette JM, Ikramuddin J, Bresinsky M, Nelson KM, Liao D, Ashe KH, Walters MA, Pockes S. Singh G, et al. ACS Chem Neurosci. 2022 May 18;13(10):1549-1557. doi: 10.1021/acschemneuro.2c00100. Epub 2022 May 6. ACS Chem Neurosci. 2022. PMID: 35522720 Free PMC article.
ALARM NMR for HTS triage and chemical probe validation.
Dahlin JL, Cuellar M, Singh G, Nelson KM, Strasser J, Rappe T, Xia Y, Veglia G, Walters MA. Dahlin JL, et al. Among authors: singh g. Curr Protoc Chem Biol. 2018 Mar;10(1):91-117. doi: 10.1002/cpch.35. Epub 2018 Apr 9. Curr Protoc Chem Biol. 2018. PMID: 30034947 Free PMC article.
The Essential Medicinal Chemistry of Cannabidiol (CBD).
Nelson KM, Bisson J, Singh G, Graham JG, Chen SN, Friesen JB, Dahlin JL, Niemitz M, Walters MA, Pauli GF. Nelson KM, et al. Among authors: singh g. J Med Chem. 2020 Nov 12;63(21):12137-12155. doi: 10.1021/acs.jmedchem.0c00724. Epub 2020 Sep 10. J Med Chem. 2020. PMID: 32804502 Free PMC article. Review.
Promotion of Cardiovascular Health in Africa: The Alliance for Medical Research in Africa (AMedRA) Expert Panel.
Ka MM, Gaye ND, Ahadzi D, Baker-Smith CM, Ndao SCT, Wambugu V, Singh G, Gueye K, Seck D, Dia K, Allen NB, Ba A, Mboup WN, Yassine R, Guissé PM, Anne M, Aw F, Bèye SM, Diouf MT, Diaw M, Belkhadir J, Wone I, Kohen JE, Mbaye MN, Ngaide AA, Liyong EA, Sougou NM, Lalika M, Ale BM, Jaiteh L, Mekonnen D, Bukachi F, Lorenz T, Ntabadde K, Mampuya W, Houinato D, Kitara DL, Kane A, Seck SM, Fall IS, Tshilolo L, Samb A, Owolabi M, Diouf M, Lamptey R, Kengne AP, Maffia P, Clifford GD, Sattler ELP, Mboup MC, Jobe M, Gaye B. Ka MM, et al. Among authors: singh g. JACC Adv. 2024 Nov 20;3(12):101376. doi: 10.1016/j.jacadv.2024.101376. eCollection 2024 Dec. JACC Adv. 2024. PMID: 39817059 Free PMC article. Review.
Docetaxel and Niclosamide-loaded Nanofiber systems for Improved Chemo-therapeutic Activity and Resistance Reversal in Prostate Cancer.
Shah S, Famta P, Vambhurkar G, Kumar R, Pandey G, Singh G, Wagh S, Kanaujiya S, Arya DK, Sharma A, Shinde A, Bhanu Prasad S, Chandankar S, Shinde S, Sharma A, Rajinikanth PS, Khatri DK, Asthana A, Srivastava S. Shah S, et al. Among authors: singh g. Drug Dev Ind Pharm. 2025 Jan 15:1-14. doi: 10.1080/03639045.2025.2453533. Online ahead of print. Drug Dev Ind Pharm. 2025. PMID: 39815752
8,489 results