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Page 1
Characterisation of a nucleo-adhesome.
Byron A, Griffith BGC, Herrero A, Loftus AEP, Koeleman ES, Kogerman L, Dawson JC, McGivern N, Culley J, Grimes GR, Serrels B, von Kriegsheim A, Brunton VG, Frame MC. Byron A, et al. Among authors: dawson jc. Nat Commun. 2022 Jun 1;13(1):3053. doi: 10.1038/s41467-022-30556-5. Nat Commun. 2022. PMID: 35650196 Free PMC article.
Rapid Discovery and Structure-Activity Relationships of Pyrazolopyrimidines That Potently Suppress Breast Cancer Cell Growth via SRC Kinase Inhibition with Exceptional Selectivity over ABL Kinase.
Fraser C, Dawson JC, Dowling R, Houston DR, Weiss JT, Munro AF, Muir M, Harrington L, Webster SP, Frame MC, Brunton VG, Patton EE, Carragher NO, Unciti-Broceta A. Fraser C, et al. Among authors: dawson jc. J Med Chem. 2016 May 26;59(10):4697-710. doi: 10.1021/acs.jmedchem.6b00065. Epub 2016 May 4. J Med Chem. 2016. PMID: 27115835 Free PMC article.
Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches.
Byrne KM, Monsefi N, Dawson JC, Degasperi A, Bukowski-Wills JC, Volinsky N, Dobrzyński M, Birtwistle MR, Tsyganov MA, Kiyatkin A, Kida K, Finch AJ, Carragher NO, Kolch W, Nguyen LK, von Kriegsheim A, Kholodenko BN. Byrne KM, et al. Among authors: dawson jc. Cell Syst. 2016 Jan 27;2(1):38-48. doi: 10.1016/j.cels.2016.01.003. Epub 2016 Jan 27. Cell Syst. 2016. PMID: 27136688 Free PMC article.
Kindlin-1 Promotes Pulmonary Breast Cancer Metastasis.
Sarvi S, Patel H, Li J, Dodd GL, Creedon H, Muir M, Ward J, Dawson JC, Lee M, Culley J, Salter DM, Sims AH, Byron A, Brunton VG. Sarvi S, et al. Among authors: dawson jc. Cancer Res. 2018 Mar 15;78(6):1484-1496. doi: 10.1158/0008-5472.CAN-17-1518. Epub 2018 Jan 12. Cancer Res. 2018. PMID: 29330144 Free PMC article.
Development of a fluorescence-based cellular apoptosis reporter.
Balderstone LA, Dawson JC, Welman A, Serrels A, Wedge SR, Brunton VG. Balderstone LA, et al. Among authors: dawson jc. Methods Appl Fluoresc. 2018 Oct 24;7(1):015001. doi: 10.1088/2050-6120/aae6f8. Methods Appl Fluoresc. 2018. PMID: 30353887 Free PMC article.
Targeting FAK in anticancer combination therapies.
Dawson JC, Serrels A, Stupack DG, Schlaepfer DD, Frame MC. Dawson JC, et al. Nat Rev Cancer. 2021 May;21(5):313-324. doi: 10.1038/s41568-021-00340-6. Epub 2021 Mar 17. Nat Rev Cancer. 2021. PMID: 33731845 Free PMC article. Review.
A Conformation Selective Mode of Inhibiting SRC Improves Drug Efficacy and Tolerability.
Temps C, Lietha D, Webb ER, Li XF, Dawson JC, Muir M, Macleod KG, Valero T, Munro AF, Contreras-Montoya R, Luque-Ortega JR, Fraser C, Beetham H, Schoenherr C, Lopalco M, Arends MJ, Frame MC, Qian BZ, Brunton VG, Carragher NO, Unciti-Broceta A. Temps C, et al. Among authors: dawson jc. Cancer Res. 2021 Nov 1;81(21):5438-5450. doi: 10.1158/0008-5472.CAN-21-0613. Epub 2021 Aug 20. Cancer Res. 2021. PMID: 34417202 Free PMC article.
61 results