Frame MC - Search Results

1

Byron A, Griffith BGC, Herrero A, Loftus AEP, Koeleman ES, Kogerman L, Dawson JC, McGivern N, Culley J, Grimes GR, Serrels B, von Kriegsheim A, Brunton VG, Frame MC. Byron A, et al. Among authors: frame mc. Nat Commun. 2022 Jun 1;13(1):3053. doi: 10.1038/s41467-022-30556-5. Nat Commun. 2022. PMID: 35650196 Free PMC article.

2

Advances in Rho-dependent actin regulation and oncogenic transformation.

Frame MC, Brunton VG. Frame MC, et al. Curr Opin Genet Dev. 2002 Feb;12(1):36-43. doi: 10.1016/s0959-437x(01)00261-1. Curr Opin Genet Dev. 2002. PMID: 11790552 Review.

3

Src-induced de-regulation of E-cadherin in colon cancer cells requires integrin signalling.

Avizienyte E, Wyke AW, Jones RJ, McLean GW, Westhoff MA, Brunton VG, Frame MC. Avizienyte E, et al. Among authors: frame mc. Nat Cell Biol. 2002 Aug;4(8):632-8. doi: 10.1038/ncb829. Nat Cell Biol. 2002. PMID: 12134161

4

Src SH3/2 domain-mediated peripheral accumulation of Src and phospho-myosin is linked to deregulation of E-cadherin and the epithelial-mesenchymal transition.

Avizienyte E, Fincham VJ, Brunton VG, Frame MC. Avizienyte E, et al. Among authors: frame mc. Mol Biol Cell. 2004 Jun;15(6):2794-803. doi: 10.1091/mbc.e03-12-0879. Epub 2004 Apr 9. Mol Biol Cell. 2004. PMID: 15075377 Free PMC article.

5

RhoB and actin polymerization coordinate Src activation with endosome-mediated delivery to the membrane.

Sandilands E, Cans C, Fincham VJ, Brunton VG, Mellor H, Prendergast GC, Norman JC, Superti-Furga G, Frame MC. Sandilands E, et al. Among authors: frame mc. Dev Cell. 2004 Dec;7(6):855-69. doi: 10.1016/j.devcel.2004.09.019. Dev Cell. 2004. PMID: 15572128 Free article.

6

Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression.

McLean GW, Komiyama NH, Serrels B, Asano H, Reynolds L, Conti F, Hodivala-Dilke K, Metzger D, Chambon P, Grant SG, Frame MC. McLean GW, et al. Among authors: frame mc. Genes Dev. 2004 Dec 15;18(24):2998-3003. doi: 10.1101/gad.316304. Genes Dev. 2004. PMID: 15601818 Free PMC article.

7

Identification of Src-specific phosphorylation site on focal adhesion kinase: dissection of the role of Src SH2 and catalytic functions and their consequences for tumor cell behavior.

Brunton VG, Avizienyte E, Fincham VJ, Serrels B, Metcalf CA 3rd, Sawyer TK, Frame MC. Brunton VG, et al. Among authors: frame mc. Cancer Res. 2005 Feb 15;65(4):1335-42. doi: 10.1158/0008-5472.CAN-04-1949. Cancer Res. 2005. PMID: 15735019

8

The SRC-induced mesenchymal state in late-stage colon cancer cells.

Avizienyte E, Brunton VG, Fincham VJ, Frame MC. Avizienyte E, et al. Among authors: frame mc. Cells Tissues Organs. 2005;179(1-2):73-80. doi: 10.1159/000084511. Cells Tissues Organs. 2005. PMID: 15942195 Review.

9

The role of focal-adhesion kinase in cancer - a new therapeutic opportunity.

McLean GW, Carragher NO, Avizienyte E, Evans J, Brunton VG, Frame MC. McLean GW, et al. Among authors: frame mc. Nat Rev Cancer. 2005 Jul;5(7):505-15. doi: 10.1038/nrc1647. Nat Rev Cancer. 2005. PMID: 16069815 Review.

10

Identification of potential biomarkers for measuring inhibition of Src kinase activity in colon cancer cells following treatment with dasatinib.

Serrels A, Macpherson IR, Evans TR, Lee FY, Clark EA, Sansom OJ, Ashton GH, Frame MC, Brunton VG. Serrels A, et al. Among authors: frame mc. Mol Cancer Ther. 2006 Dec;5(12):3014-22. doi: 10.1158/1535-7163.MCT-06-0382. Epub 2006 Dec 5. Mol Cancer Ther. 2006. PMID: 17148760

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