Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia.
Agoro R, Montagna A, Goetz R, Aligbe O, Singh G, Coe LM, Mohammadi M, Rivella S, Sitara D.
Agoro R, et al.
FASEB J. 2018 Jul;32(7):3752-3764. doi: 10.1096/fj.201700667R. Epub 2018 Feb 26.
FASEB J. 2018.
PMID: 29481308
Free PMC article.
Our data clearly demonstrate that elevated FGF23 is a causative factor in the development of renal anemia and iron deficiency, and importantly, blocking FGF23 signaling represents a novel approach to stimulate erythropoiesis and possibly improve survival for millions of chronic k …
Our data clearly demonstrate that elevated FGF23 is a causative factor in the development of renal anemia and iron deficiency, and important …