Kanaar R - Search Results

1

Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.

Meijer TG, Nguyen L, Van Hoeck A, Sieuwerts AM, Verkaik NS, Ladan MM, Ruigrok-Ritstier K, van Deurzen CHM, van de Werken HJG, Lips EH, Linn SC, Memari Y, Davies H, Nik-Zainal S, Kanaar R, Martens JWM, Cuppen E, Jager A, van Gent DC. Meijer TG, et al. Among authors: kanaar r. Oncogene. 2022 Jun;41(26):3498-3506. doi: 10.1038/s41388-022-02363-1. Epub 2022 Jun 3. Oncogene. 2022. PMID: 35662281 Free PMC article.

2

Molecular mechanisms of DNA double strand break repair.

Kanaar R, Hoeijmakers JH, van Gent DC. Kanaar R, et al. Trends Cell Biol. 1998 Dec;8(12):483-9. doi: 10.1016/s0962-8924(98)01383-x. Trends Cell Biol. 1998. PMID: 9861670 Review.

3

DNA-binding and strand-annealing activities of human Mre11: implications for its roles in DNA double-strand break repair pathways.

de Jager M, Dronkert ML, Modesti M, Beerens CE, Kanaar R, van Gent DC. de Jager M, et al. Among authors: kanaar r. Nucleic Acids Res. 2001 Mar 15;29(6):1317-25. doi: 10.1093/nar/29.6.1317. Nucleic Acids Res. 2001. PMID: 11238998 Free PMC article.

4

Chromosomal stability and the DNA double-stranded break connection.

van Gent DC, Hoeijmakers JH, Kanaar R. van Gent DC, et al. Among authors: kanaar r. Nat Rev Genet. 2001 Mar;2(3):196-206. doi: 10.1038/35056049. Nat Rev Genet. 2001. PMID: 11256071 Review.

5

Homologous recombination: from model organisms to human disease.

Modesti M, Kanaar R. Modesti M, et al. Among authors: kanaar r. Genome Biol. 2001;2(5):REVIEWS1014. doi: 10.1186/gb-2001-2-5-reviews1014. Epub 2001 Apr 26. Genome Biol. 2001. PMID: 11387040 Free PMC article. Review.

6

Human Rad50/Mre11 is a flexible complex that can tether DNA ends.

de Jager M, van Noort J, van Gent DC, Dekker C, Kanaar R, Wyman C. de Jager M, et al. Among authors: kanaar r. Mol Cell. 2001 Nov;8(5):1129-35. doi: 10.1016/s1097-2765(01)00381-1. Mol Cell. 2001. PMID: 11741547 Free article.

7

DNA end-binding specificity of human Rad50/Mre11 is influenced by ATP.

de Jager M, Wyman C, van Gent DC, Kanaar R. de Jager M, et al. Among authors: kanaar r. Nucleic Acids Res. 2002 Oct 15;30(20):4425-31. doi: 10.1093/nar/gkf574. Nucleic Acids Res. 2002. PMID: 12384589 Free PMC article.

8

NBS1 cooperates with homologous recombination to counteract chromosome breakage during replication.

Brugmans L, Verkaik NS, Kunen M, van Drunen E, Williams BR, Petrini JH, Kanaar R, Essers J, van Gent DC. Brugmans L, et al. Among authors: kanaar r. DNA Repair (Amst). 2009 Dec 3;8(12):1363-70. doi: 10.1016/j.dnarep.2009.09.002. Epub 2009 Sep 25. DNA Repair (Amst). 2009. PMID: 19782649 Free PMC article.

9

BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells.

Chu WK, Hanada K, Kanaar R, Hickson ID. Chu WK, et al. Among authors: kanaar r. Oncogene. 2010 Aug 19;29(33):4705-14. doi: 10.1038/onc.2010.214. Epub 2010 Jun 7. Oncogene. 2010. PMID: 20531307

10

Hyperthermia-induced DNA repair deficiency suggests novel therapeutic anti-cancer strategies.

Eppink B, Krawczyk PM, Stap J, Kanaar R. Eppink B, et al. Among authors: kanaar r. Int J Hyperthermia. 2012;28(6):509-17. doi: 10.3109/02656736.2012.695427. Epub 2012 Jul 26. Int J Hyperthermia. 2012. PMID: 22834701 Free article. Review.

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