Buchholz CJ - Search Results

1

APPsα Rescues Tau-Induced Synaptic Pathology.

Bold CS, Baltissen D, Ludewig S, Back MK, Just J, Kilian L, Erdinger S, Banicevic M, Rehra L, Almouhanna F, Nigri M, Wolfer DP, Spilger R, Rohr K, Kann O, Buchholz CJ, von Engelhardt J, Korte M, Müller UC. Bold CS, et al. Among authors: buchholz cj. J Neurosci. 2022 Jul 20;42(29):5782-5802. doi: 10.1523/JNEUROSCI.2200-21.2022. Epub 2022 Jun 6. J Neurosci. 2022. PMID: 35667850 Free PMC article.

2

The secreted beta-amyloid precursor protein ectodomain APPs alpha is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice.

Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA, Herms J, Buchholz C, Eckman CB, Korte M, Wolfer DP, Müller UC. Ring S, et al. J Neurosci. 2007 Jul 18;27(29):7817-26. doi: 10.1523/JNEUROSCI.1026-07.2007. J Neurosci. 2007. PMID: 17634375 Free PMC article.

3

Vaccination with Abeta-displaying virus-like particles reduces soluble and insoluble cerebral Abeta and lowers plaque burden in APP transgenic mice.

Bach P, Tschäpe JA, Kopietz F, Braun G, Baade JK, Wiederhold KH, Staufenbiel M, Prinz M, Deller T, Kalinke U, Buchholz CJ, Müller UC. Bach P, et al. Among authors: buchholz cj. J Immunol. 2009 Jun 15;182(12):7613-24. doi: 10.4049/jimmunol.0803366. J Immunol. 2009. PMID: 19494285

4

Specific gene transfer to neurons, endothelial cells and hematopoietic progenitors with lentiviral vectors.

Anliker B, Abel T, Kneissl S, Hlavaty J, Caputi A, Brynza J, Schneider IC, Münch RC, Petznek H, Kontermann RE, Koehl U, Johnston IC, Keinänen K, Müller UC, Hohenadl C, Monyer H, Cichutek K, Buchholz CJ. Anliker B, et al. Among authors: buchholz cj. Nat Methods. 2010 Nov;7(11):929-35. doi: 10.1038/nmeth.1514. Epub 2010 Oct 10. Nat Methods. 2010. PMID: 20935652

5

Specific gene delivery to liver sinusoidal and artery endothelial cells.

Abel T, El Filali E, Waern J, Schneider IC, Yuan Q, Münch RC, Hick M, Warnecke G, Madrahimov N, Kontermann RE, Schüttrumpf J, Müller UC, Seppen J, Ott M, Buchholz CJ. Abel T, et al. Among authors: buchholz cj. Blood. 2013 Sep 19;122(12):2030-8. doi: 10.1182/blood-2012-11-468579. Epub 2013 Jul 24. Blood. 2013. PMID: 23884859 Free article.

6

Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway.

Milosch N, Tanriöver G, Kundu A, Rami A, François JC, Baumkötter F, Weyer SW, Samanta A, Jäschke A, Brod F, Buchholz CJ, Kins S, Behl C, Müller UC, Kögel D. Milosch N, et al. Among authors: buchholz cj. Cell Death Dis. 2014 Aug 28;5(8):e1391. doi: 10.1038/cddis.2014.352. Cell Death Dis. 2014. PMID: 25165877 Free PMC article.

7

Viral gene transfer of APPsα rescues synaptic failure in an Alzheimer's disease mouse model.

Fol R, Braudeau J, Ludewig S, Abel T, Weyer SW, Roederer JP, Brod F, Audrain M, Bemelmans AP, Buchholz CJ, Korte M, Cartier N, Müller UC. Fol R, et al. Among authors: buchholz cj. Acta Neuropathol. 2016 Feb;131(2):247-266. doi: 10.1007/s00401-015-1498-9. Epub 2015 Nov 4. Acta Neuropathol. 2016. PMID: 26538149

8

Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition.

Richter MC, Ludewig S, Winschel A, Abel T, Bold C, Salzburger LR, Klein S, Han K, Weyer SW, Fritz AK, Laube B, Wolfer DP, Buchholz CJ, Korte M, Müller UC. Richter MC, et al. Among authors: buchholz cj. EMBO J. 2018 Jun 1;37(11):e98335. doi: 10.15252/embj.201798335. Epub 2018 Apr 16. EMBO J. 2018. PMID: 29661886 Free PMC article.

9

APPsα rescues CDK5 and GSK3β dysregulation and restores normal spine density in Tau transgenic mice.

Baltissen D, Bold CS, Rehra L, Banićević M, Fricke J, Just J, Ludewig S, Buchholz CJ, Korte M, Müller UC. Baltissen D, et al. Among authors: buchholz cj. Front Cell Neurosci. 2023 Jan 26;17:1106176. doi: 10.3389/fncel.2023.1106176. eCollection 2023. Front Cell Neurosci. 2023. PMID: 36779015 Free PMC article.

10

Substantially improved gene transfer to interneurons with second-generation glutamate receptor-targeted DART-AAV vectors.

Günther DM, Kovacs R, Wildner F, Salivara A, Thalheimer FB, Fries P, Geiger JRP, Buchholz CJ. Günther DM, et al. Among authors: buchholz cj. J Neurosci Methods. 2023 Nov 1;399:109981. doi: 10.1016/j.jneumeth.2023.109981. Epub 2023 Sep 30. J Neurosci Methods. 2023. PMID: 37783350 Free article.

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