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Diastereoselectivity is in the Details: Minor Changes Yield Major Improvements to the Synthesis of Bedaquiline.
Chemistry. 2022 Aug 22;28(47):e202201311. doi: 10.1002/chem.202201311. Epub 2022 Jul 7.
Chemistry. 2022.
PMID: 35675114
Free PMC article.
Progress Toward a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine.
Ahlqvist GP, McGeough CP, Senanayake C, Armstrong JD, Yadaw A, Roy S, Ahmad S, Snead DR, Jamison TF.
Ahlqvist GP, et al.
ACS Omega. 2021 Apr 8;6(15):10396-10402. doi: 10.1021/acsomega.1c00772. eCollection 2021 Apr 20.
ACS Omega. 2021.
PMID: 34056192
Free PMC article.
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A concise route to MK-4482 (EIDD-2801) from cytidine.
Vasudevan N , Ahlqvist GP , McGeough CP , Paymode DJ , Cardoso FSP , Lucas T , Dietz JP , Opatz T , Jamison TF , Gupton FB , Snead DR .
Vasudevan N , et al. Among authors: ahlqvist gp.
Chem Commun (Camb). 2020 Nov 11;56(87):13363-13364. doi: 10.1039/d0cc05944g. Epub 2020 Oct 8.
Chem Commun (Camb). 2020.
PMID: 33030468
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