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ATR-mediated CD47 and PD-L1 up-regulation restricts radiotherapy-induced immune priming and abscopal responses in colorectal cancer.
Hsieh RC, Krishnan S, Wu RC, Boda AR, Liu A, Winkler M, Hsu WH, Lin SH, Hung MC, Chan LC, Bhanu KR, Srinivasamani A, De Azevedo RA, Chou YC, DePinho RA, Gubin M, Vilar E, Chen CH, Slay R, Jayaprakash P, Hegde SM, Hartley G, Lea ST, Prasad R, Morrow B, Couillault CA, Steiner M, Wang CC, Venkatesulu BP, Taniguchi C, Kim YSB, Chen J, Rudqvist NP, Curran MA. Hsieh RC, et al. Among authors: rudqvist np. Sci Immunol. 2022 Jun 10;7(72):eabl9330. doi: 10.1126/sciimmunol.abl9330. Epub 2022 Jun 10. Sci Immunol. 2022. PMID: 35687697 Free PMC article.
Radiotherapy-exposed CD8+ and CD4+ neoantigens enhance tumor control.
Lhuillier C, Rudqvist NP, Yamazaki T, Zhang T, Charpentier M, Galluzzi L, Dephoure N, Clement CC, Santambrogio L, Zhou XK, Formenti SC, Demaria S. Lhuillier C, et al. Among authors: rudqvist np. J Clin Invest. 2021 Mar 1;131(5):e138740. doi: 10.1172/JCI138740. J Clin Invest. 2021. PMID: 33476307 Free PMC article.
Radiotherapy induces responses of lung cancer to CTLA-4 blockade.
Formenti SC, Rudqvist NP, Golden E, Cooper B, Wennerberg E, Lhuillier C, Vanpouille-Box C, Friedman K, Ferrari de Andrade L, Wucherpfennig KW, Heguy A, Imai N, Gnjatic S, Emerson RO, Zhou XK, Zhang T, Chachoua A, Demaria S. Formenti SC, et al. Among authors: rudqvist np. Nat Med. 2018 Dec;24(12):1845-1851. doi: 10.1038/s41591-018-0232-2. Epub 2018 Nov 5. Nat Med. 2018. PMID: 30397353 Free PMC article. Clinical Trial.
Hallmarks of Resistance to Immune-Checkpoint Inhibitors.
Karasarides M, Cogdill AP, Robbins PB, Bowden M, Burton EM, Butterfield LH, Cesano A, Hammer C, Haymaker CL, Horak CE, McGee HM, Monette A, Rudqvist NP, Spencer CN, Sweis RF, Vincent BG, Wennerberg E, Yuan J, Zappasodi R, Lucey VMH, Wells DK, LaVallee T. Karasarides M, et al. Among authors: rudqvist np. Cancer Immunol Res. 2022 Apr 1;10(4):372-383. doi: 10.1158/2326-6066.CIR-20-0586. Cancer Immunol Res. 2022. PMID: 35362046 Free PMC article.
Pipeline to identify neoantigens exposed by radiation.
Lhuillier C, Van Nest SJ, Rudqvist NP, Demaria S. Lhuillier C, et al. Among authors: rudqvist np. Methods Cell Biol. 2023;180:25-37. doi: 10.1016/bs.mcb.2023.02.010. Epub 2023 Apr 6. Methods Cell Biol. 2023. PMID: 37890930
32 results