Shen Y - Search Results

1

Biosynthesis of Glidomides and Elucidation of Different Mechanisms for Formation of β-OH Amino Acid Building Blocks.

Chen H, Zhong L, Zhou H, Sun T, Zhong G, Tu Q, Zhuang Y, Bai X, Wang X, Xu J, Xia L, Shen Y, Zhang Y, Bian X. Chen H, et al. Among authors: shen y. Angew Chem Int Ed Engl. 2022 Aug 26;61(35):e202203591. doi: 10.1002/anie.202203591. Epub 2022 Jun 29. Angew Chem Int Ed Engl. 2022. PMID: 35689369

2

Iterative assembly of two separate polyketide chains by the same single-module bacterial polyketide synthase in the biosynthesis of HSAF.

Li Y, Chen H, Ding Y, Xie Y, Wang H, Cerny RL, Shen Y, Du L. Li Y, et al. Among authors: shen y. Angew Chem Int Ed Engl. 2014 Jul 14;53(29):7524-7530. doi: 10.1002/anie.201403500. Epub 2014 May 30. Angew Chem Int Ed Engl. 2014. PMID: 24890524 Free PMC article.

3

Heterologous Production and Yield Improvement of Epothilones in Burkholderiales Strain DSM 7029.

Bian X, Tang B, Yu Y, Tu Q, Gross F, Wang H, Li A, Fu J, Shen Y, Li YZ, Stewart AF, Zhao G, Ding X, Müller R, Zhang Y. Bian X, et al. Among authors: shen y. ACS Chem Biol. 2017 Jul 21;12(7):1805-1812. doi: 10.1021/acschembio.7b00097. Epub 2017 May 18. ACS Chem Biol. 2017. PMID: 28467833

4

Yield improvement of epothilones in Burkholderia strain DSM7029 via transporter engineering.

Liu C, Yu F, Liu Q, Bian X, Hu S, Yang H, Yin Y, Li Y, Shen Y, Xia L, Tu Q, Zhang Y. Liu C, et al. Among authors: shen y. FEMS Microbiol Lett. 2018 May 1;365(9). doi: 10.1093/femsle/fny045. FEMS Microbiol Lett. 2018. PMID: 29529178

5

Heterologous Expression Guides Identification of the Biosynthetic Gene Cluster of Chuangxinmycin, an Indole Alkaloid Antibiotic.

Xu X, Zhou H, Liu Y, Liu X, Fu J, Li A, Li YZ, Shen Y, Bian X, Zhang Y. Xu X, et al. Among authors: shen y. J Nat Prod. 2018 Apr 27;81(4):1060-1064. doi: 10.1021/acs.jnatprod.7b00835. Epub 2018 Mar 22. J Nat Prod. 2018. PMID: 29565122

6

Discovery of recombinases enables genome mining of cryptic biosynthetic gene clusters in Burkholderiales species.

Wang X, Zhou H, Chen H, Jing X, Zheng W, Li R, Sun T, Liu J, Fu J, Huo L, Li YZ, Shen Y, Ding X, Müller R, Bian X, Zhang Y. Wang X, et al. Among authors: shen y. Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4255-E4263. doi: 10.1073/pnas.1720941115. Epub 2018 Apr 16. Proc Natl Acad Sci U S A. 2018. PMID: 29666226 Free PMC article.

7

Enzymatic O-Glycosylation of Etoposide Aglycone by Exploration of the Substrate Promiscuity for Glycosyltransferases.

Jia KZ, Zhu LW, Qu X, Li S, Shen Y, Qi Q, Zhang Y, Li YZ, Tang YJ. Jia KZ, et al. Among authors: shen y. ACS Synth Biol. 2019 Dec 20;8(12):2718-2725. doi: 10.1021/acssynbio.9b00318. Epub 2019 Dec 10. ACS Synth Biol. 2019. PMID: 31774653

8

Challenges and potential for improving the druggability of podophyllotoxin-derived drugs in cancer chemotherapy.

Zhao W, Cong Y, Li HM, Li S, Shen Y, Qi Q, Zhang Y, Li YZ, Tang YJ. Zhao W, et al. Among authors: shen y. Nat Prod Rep. 2021 Mar 1;38(3):470-488. doi: 10.1039/d0np00041h. Epub 2020 Sep 8. Nat Prod Rep. 2021. PMID: 32895676 Review.

9

Triazole/thiadiazole substituted 4'-demethylepipodophyllotoxin derivatives induced apoptosis in HeLa cells by up-regulating TMEM133.

Zhao W, Duan Y, Li HM, Li S, Shen Y, Zhang Y, Li YZ, Tang YJ. Zhao W, et al. Among authors: shen y. Eur J Pharmacol. 2021 Aug 15;905:174189. doi: 10.1016/j.ejphar.2021.174189. Epub 2021 May 24. Eur J Pharmacol. 2021. PMID: 34033816

10

Biosynthesis of Chuangxinmycin Featuring a Deubiquitinase-like Sulfurtransferase.

Zhang X, Xu X, You C, Yang C, Guo J, Sang M, Geng C, Cheng F, Du L, Shen Y, Wang S, Lan H, Yang F, Li Y, Tang YJ, Zhang Y, Bian X, Li S, Zhang W. Zhang X, et al. Among authors: shen y. Angew Chem Int Ed Engl. 2021 Nov 8;60(46):24418-24423. doi: 10.1002/anie.202107745. Epub 2021 Oct 7. Angew Chem Int Ed Engl. 2021. PMID: 34498345

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