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Early neutralizing IgG response to Chikungunya virus in infected patients targets a dominant linear epitope on the E2 glycoprotein.
Kam YW, Lum FM, Teo TH, Lee WW, Simarmata D, Harjanto S, Chua CL, Chan YF, Wee JK, Chow A, Lin RT, Leo YS, Le Grand R, Sam IC, Tong JC, Roques P, Wiesmüller KH, Rénia L, Rötzschke O, Ng LF. Kam YW, et al. Among authors: renia l. EMBO Mol Med. 2012 Apr;4(4):330-43. doi: 10.1002/emmm.201200213. Epub 2012 Mar 5. EMBO Mol Med. 2012. PMID: 22389221 Free PMC article.
Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response.
Her Z, Teng TS, Tan JJ, Teo TH, Kam YW, Lum FM, Lee WW, Gabriel C, Melchiotti R, Andiappan AK, Lulla V, Lulla A, Win MK, Chow A, Biswas SK, Leo YS, Lecuit M, Merits A, Rénia L, Ng LF. Her Z, et al. Among authors: renia l. EMBO Mol Med. 2015 Jan;7(1):24-41. doi: 10.15252/emmm.201404459. EMBO Mol Med. 2015. PMID: 25452586 Free PMC article.
Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections.
Kam YW, Lee CY, Teo TH, Howland SW, Amrun SN, Lum FM, See P, Kng NQ, Huber RG, Xu MH, Tan HL, Choo A, Maurer-Stroh S, Ginhoux F, Fink K, Wang CI, Ng LF, Rénia L. Kam YW, et al. Among authors: renia l. JCI Insight. 2017 Apr 20;2(8):e92428. doi: 10.1172/jci.insight.92428. eCollection 2017 Apr 20. JCI Insight. 2017. PMID: 28422757 Free PMC article.
Multimodal assessments of Zika virus immune pathophysiological responses in marmosets.
Lum FM, Zhang W, Lim KC, Malleret B, Teo TH, Koh JJ, Lee KJ, Chua TK, Kam YW, Yee WX, Huen I, Tan JJL, Amrun SN, Prakash Kn B, Cozzone PJ, Renia L, Lee PTH, Ng LFP. Lum FM, et al. Among authors: renia l. Sci Rep. 2018 Nov 20;8(1):17125. doi: 10.1038/s41598-018-35481-6. Sci Rep. 2018. PMID: 30459473 Free PMC article.
The trinity of COVID-19: immunity, inflammation and intervention.
Tay MZ, Poh CM, Rénia L, MacAry PA, Ng LFP. Tay MZ, et al. Among authors: renia l. Nat Rev Immunol. 2020 Jun;20(6):363-374. doi: 10.1038/s41577-020-0311-8. Epub 2020 Apr 28. Nat Rev Immunol. 2020. PMID: 32346093 Free PMC article. Review.
420 results