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494 results

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Page 1
Deregulation and epigenetic modification of BCL2-family genes cause resistance to venetoclax in hematologic malignancies.
Thomalla D, Beckmann L, Grimm C, Oliverio M, Meder L, Herling CD, Nieper P, Feldmann T, Merkel O, Lorsy E, da Palma Guerreiro A, von Jan J, Kisis I, Wasserburger E, Claasen J, Faitschuk-Meyer E, Altmüller J, Nürnberg P, Yang TP, Lienhard M, Herwig R, Kreuzer KA, Pallasch CP, Büttner R, Schäfer SC, Hartley J, Abken H, Peifer M, Kashkar H, Knittel G, Eichhorst B, Ullrich RT, Herling M, Reinhardt HC, Hallek M, Schweiger MR, Frenzel LP. Thomalla D, et al. Among authors: buttner r. Blood. 2022 Nov 17;140(20):2113-2126. doi: 10.1182/blood.2021014304. Blood. 2022. PMID: 35704690 Free PMC article.
Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer.
Malchers F, Nogova L, van Attekum MH, Maas L, Brägelmann J, Bartenhagen C, Girard L, Bosco G, Dahmen I, Michels S, Weeden CE, Scheel AH, Meder L, Golfmann K, Schuldt P, Siemanowski J, Rehker J, Merkelbach-Bruse S, Menon R, Gautschi O, Heuckmann JM, Brambilla E, Asselin-Labat ML, Persigehl T, Minna JD, Walczak H, Ullrich RT, Fischer M, Reinhardt HC, Wolf J, Büttner R, Peifer M, George J, Thomas RK. Malchers F, et al. Among authors: buttner r. J Clin Invest. 2023 Nov 1;133(21):e170217. doi: 10.1172/JCI170217. J Clin Invest. 2023. PMID: 37606995 Free PMC article.
Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis.
Meder L, Orschel CI, Otto CJ, Koker M, Brägelmann J, Ercanoglu MS, Dähling S, Compes A, Selenz C, Nill M, Dietlein F, Florin A, Eich ML, Borchmann S, Odenthal M, Blazquez R, Hilberg F, Klein F, Hallek M, Büttner R, Reinhardt HC, Ullrich RT. Meder L, et al. Among authors: buttner r. JCI Insight. 2024 May 22;9(10):e166402. doi: 10.1172/jci.insight.166402. JCI Insight. 2024. PMID: 38775153 Free PMC article.
Macrophages are activated toward phagocytic lymphoma cell clearance by pentose phosphate pathway inhibition.
Beielstein AC, Izquierdo E, Blakemore S, Nickel N, Michalik M, Chawan S, Brinker R, Bartel HH, Vorholt D, Albert L, Nolte JL, Linke R, Costa Picossi CR, Sáiz J, Picard F, Florin A, Meinel J, Büttner R, Diefenhardt P, Brähler S, Villaseñor A, Winkels H, Hallek M, Krüger M, Barbas C, Pallasch CP. Beielstein AC, et al. Among authors: buttner r. Cell Rep Med. 2024 Dec 17;5(12):101830. doi: 10.1016/j.xcrm.2024.101830. Epub 2024 Nov 26. Cell Rep Med. 2024. PMID: 39603243 Free article.
Telomerase Is a Prognostic Marker of Poor Outcome and a Therapeutic Target in Neuroblastoma.
Roderwieser A, Sand F, Walter E, Fischer J, Gecht J, Bartenhagen C, Ackermann S, Otte F, Welte A, Kahlert Y, Lieberz D, Hertwig F, Reinhardt HC, Simon T, Peifer M, Ortmann M, Büttner R, Hero B, O'Sullivan RJ, Berthold F, Fischer M. Roderwieser A, et al. Among authors: buttner r. JCO Precis Oncol. 2019 Dec;3:1-20. doi: 10.1200/PO.19.00072. JCO Precis Oncol. 2019. PMID: 35100718
A novel mouse model recapitulating the MMR-defective SCLC subtype uncovers an actionable sensitivity to immune checkpoint blockade.
Ibruli O, Rose F, Beleggia F, Schmitt A, Cartolano M, Fernandez LT, Saggau J, Bonasera D, Kiljan M, Gozum G, Lichius L, Cai J, Niu LN, Caiaffa MI, Herter JM, Walczak H, Liccardi G, Grüll H, Büttner R, Bosco G, George J, Thomas RK, Bozek K, Reinhardt HC, Herter-Sprie GS. Ibruli O, et al. Among authors: buttner r. J Cancer Res Clin Oncol. 2024 Nov 14;150(11):496. doi: 10.1007/s00432-024-05942-9. J Cancer Res Clin Oncol. 2024. PMID: 39542886 Free PMC article.
MET Fusions in NSCLC: Clinicopathologic Features and Response to MET Inhibition.
Riedel R, Fassunke J, Scheel AH, Scheffler M, Heydt C, Nogova L, Michels S, Fischer RN, Eisert A, Scharpenseel H, John F, Ruge L, Schaufler D, Siemanowski J, Ihle MA, Wagener-Ryczek S, Pappesch R, Rehker J, Bunck A, Kobe C, Keil F, Merkelbach-Bruse S, Büttner R, Wolf J. Riedel R, et al. Among authors: buttner r. J Thorac Oncol. 2024 Jan;19(1):160-165. doi: 10.1016/j.jtho.2023.06.020. Epub 2023 Jul 8. J Thorac Oncol. 2024. PMID: 37429463
A genomics-based classification of human lung tumors.
Clinical Lung Cancer Genome Project (CLCGP); Network Genomic Medicine (NGM). Clinical Lung Cancer Genome Project (CLCGP), et al. Sci Transl Med. 2013 Oct 30;5(209):209ra153. doi: 10.1126/scitranslmed.3006802. Sci Transl Med. 2013. PMID: 24174329 Free PMC article.
Resistance to MET inhibition in MET-dependent NSCLC and therapeutic activity after switching from type I to type II MET inhibitors.
Riedel R, Fassunke J, Tumbrink HL, Scheel AH, Heydt C, Hieggelke L, Scheffler M, Heimsoeth A, Nogova L, Michels S, Weber JP, Fischer RN, Eisert A, Westphal T, Schaufler D, Siemanowski J, Ihle MA, Wagener-Ryczek S, Castiglione R, Pappesch R, Rehker J, Jürgens J, Stoelben E, Bunck A, Kobe C, Merkelbach-Bruse S, Sos ML, Büttner R, Wolf J. Riedel R, et al. Among authors: buttner r. Eur J Cancer. 2023 Jan;179:124-135. doi: 10.1016/j.ejca.2022.11.010. Epub 2022 Nov 15. Eur J Cancer. 2023. PMID: 36521334
Do skip-N2 metastases significantly impact overall survival and disease-free interval in N2 non-small-cell lung cancer patients? A multicentre analysis.
Schlachtenberger G, Schallenberg S, Doerr F, Menghesha H, Gaisendrees C, Amorin A, Grathwohl C, Büttner R, Quaas A, Horst D, Klauschen F, Frost N, Rueckert JC, Neudecker J, Höpker K, Wahlers T, Hekmat K, Heldwein MB. Schlachtenberger G, et al. Among authors: buttner r. Eur J Cardiothorac Surg. 2023 Jul 3;64(1):ezad247. doi: 10.1093/ejcts/ezad247. Eur J Cardiothorac Surg. 2023. PMID: 37369037
494 results