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549 results

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Page 1
Identifying the Common Genetic Basis of Antidepressant Response.
Pain O, Hodgson K, Trubetskoy V, Ripke S, Marshe VS, Adams MJ, Byrne EM, Campos AI, Carrillo-Roa T, Cattaneo A, Als TD, Souery D, Dernovsek MZ, Fabbri C, Hayward C, Henigsberg N, Hauser J, Kennedy JL, Lenze EJ, Lewis G, Müller DJ, Martin NG, Mulsant BH, Mors O, Perroud N, Porteous DJ, Rentería ME, Reynolds CF 3rd, Rietschel M, Uher R, Wigmore EM, Maier W, Wray NR, Aitchison KJ, Arolt V, Baune BT, Biernacka JM, Bondolfi G, Domschke K, Kato M, Li QS, Liu YL, Serretti A, Tsai SJ, Turecki G, Weinshilboum R; GSRD Consortium; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; McIntosh AM, Lewis CM. Pain O, et al. Among authors: weinshilboum r. Biol Psychiatry Glob Open Sci. 2022 Apr;2(2):115-126. doi: 10.1016/j.bpsgos.2021.07.008. Biol Psychiatry Glob Open Sci. 2022. PMID: 35712048 Free PMC article.
The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response.
Biernacka JM, Sangkuhl K, Jenkins G, Whaley RM, Barman P, Batzler A, Altman RB, Arolt V, Brockmöller J, Chen CH, Domschke K, Hall-Flavin DK, Hong CJ, Illi A, Ji Y, Kampman O, Kinoshita T, Leinonen E, Liou YJ, Mushiroda T, Nonen S, Skime MK, Wang L, Baune BT, Kato M, Liu YL, Praphanphoj V, Stingl JC, Tsai SJ, Kubo M, Klein TE, Weinshilboum R. Biernacka JM, et al. Among authors: weinshilboum r. Transl Psychiatry. 2015 Apr 21;5(4):e553. doi: 10.1038/tp.2015.47. Transl Psychiatry. 2015. PMID: 25897834 Free PMC article.
Validation of the 17-item Hamilton Depression Rating Scale definition of response for adults with major depressive disorder using equipercentile linking to Clinical Global Impression scale ratings: analysis of Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study (PGRN-AMPS) data.
Bobo WV, Angleró GC, Jenkins G, Hall-Flavin DK, Weinshilboum R, Biernacka JM. Bobo WV, et al. Among authors: weinshilboum r. Hum Psychopharmacol. 2016 May;31(3):185-92. doi: 10.1002/hup.2526. Epub 2016 Mar 21. Hum Psychopharmacol. 2016. PMID: 26999588 Free PMC article.
Polymorphic variation in TPMT is the principal determinant of TPMT phenotype: A meta-analysis of three genome-wide association studies.
Tamm R, Mägi R, Tremmel R, Winter S, Mihailov E, Smid A, Möricke A, Klein K, Schrappe M, Stanulla M, Houlston R, Weinshilboum R, Mlinarič Raščan I, Metspalu A, Milani L, Schwab M, Schaeffeler E. Tamm R, et al. Among authors: weinshilboum r. Clin Pharmacol Ther. 2017 May;101(5):684-695. doi: 10.1002/cpt.540. Epub 2017 Feb 1. Clin Pharmacol Ther. 2017. PMID: 27770449 Free PMC article. Review.
Exploring hepsin functional genetic variation association with disease specific protein expression in bipolar disorder: Applications of a proteomic informed genomic approach.
Nassan M, Jia YF, Jenkins G, Colby C, Feeder S, Choi DS, Veldic M, McElroy SL, Bond DJ, Weinshilboum R, Biernacka JM, Frye MA. Nassan M, et al. Among authors: weinshilboum r. J Psychiatr Res. 2017 Dec;95:208-212. doi: 10.1016/j.jpsychires.2017.07.005. Epub 2017 Jul 4. J Psychiatr Res. 2017. PMID: 28886448
Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: Meta-analysis of three treatment cohorts.
Ward J, Graham N, Strawbridge RJ, Ferguson A, Jenkins G, Chen W, Hodgson K, Frye M, Weinshilboum R, Uher R, Lewis CM, Biernacka J, Smith DJ. Ward J, et al. Among authors: weinshilboum r. PLoS One. 2018 Sep 21;13(9):e0203896. doi: 10.1371/journal.pone.0203896. eCollection 2018. PLoS One. 2018. PMID: 30240446 Free PMC article.
Genetic contributions to alcohol use disorder treatment outcomes: a genome-wide pharmacogenomics study.
Biernacka JM, Coombes BJ, Batzler A, Ho AM, Geske JR, Frank J, Hodgkinson C, Skime M, Colby C, Zillich L, Pozsonyiova S, Ho MF, Kiefer F, Rietschel M, Weinshilboum R, O'Malley SS, Mann K, Anton R, Goldman D, Karpyak VM. Biernacka JM, et al. Among authors: weinshilboum r. Neuropsychopharmacology. 2021 Nov;46(12):2132-2139. doi: 10.1038/s41386-021-01097-0. Epub 2021 Jul 23. Neuropsychopharmacology. 2021. PMID: 34302059 Free PMC article.
Network science approach elucidates integrative genomic-metabolomic signature of antidepressant response and lifetime history of attempted suicide in adults with major depressive disorder.
Grant CW, Wilton AR, Kaddurah-Daouk R, Skime M, Biernacka J, Mayes T, Carmody T, Wang L, Lazaridis K, Weinshilboum R, Bobo WV, Trivedi MH, Croarkin PE, Athreya AP. Grant CW, et al. Among authors: weinshilboum r. Front Pharmacol. 2022 Oct 3;13:984383. doi: 10.3389/fphar.2022.984383. eCollection 2022. Front Pharmacol. 2022. PMID: 36263124 Free PMC article.
Genome-wide association studies in pharmacogenomics: successes and lessons.
Motsinger-Reif AA, Jorgenson E, Relling MV, Kroetz DL, Weinshilboum R, Cox NJ, Roden DM. Motsinger-Reif AA, et al. Among authors: weinshilboum r. Pharmacogenet Genomics. 2013 Aug;23(8):383-94. doi: 10.1097/FPC.0b013e32833d7b45. Pharmacogenet Genomics. 2013. PMID: 20639796 Free PMC article. Review.
Treatment outcomes of depression: the pharmacogenomic research network antidepressant medication pharmacogenomic study.
Mrazek DA, Biernacka JM, McAlpine DE, Benitez J, Karpyak VM, Williams MD, Hall-Flavin DK, Netzel PJ, Passov V, Rohland BM, Shinozaki G, Hoberg AA, Snyder KA, Drews MS, Skime MK, Sagen JA, Schaid DJ, Weinshilboum R, Katzelnick DJ. Mrazek DA, et al. Among authors: weinshilboum r. J Clin Psychopharmacol. 2014 Jun;34(3):313-7. doi: 10.1097/JCP.0000000000000099. J Clin Psychopharmacol. 2014. PMID: 24743713 Free PMC article. Clinical Trial.
549 results