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Egg-Derived Anti-SARS-CoV-2 Immunoglobulin Y (IgY) With Broad Variant Activity as Intranasal Prophylaxis Against COVID-19.
Frumkin LR, Lucas M, Scribner CL, Ortega-Heinly N, Rogers J, Yin G, Hallam TJ, Yam A, Bedard K, Begley R, Cohen CA, Badger CV, Abbasi SA, Dye JM, McMillan B, Wallach M, Bricker TL, Joshi A, Boon ACM, Pokhrel S, Kraemer BR, Lee L, Kargotich S, Agochiya M, John TS, Mochly-Rosen D. Frumkin LR, et al. Among authors: hallam tj. Front Immunol. 2022 Jun 1;13:899617. doi: 10.3389/fimmu.2022.899617. eCollection 2022. Front Immunol. 2022. PMID: 35720389 Free PMC article. Clinical Trial.
Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system.
Zimmerman ES, Heibeck TH, Gill A, Li X, Murray CJ, Madlansacay MR, Tran C, Uter NT, Yin G, Rivers PJ, Yam AY, Wang WD, Steiner AR, Bajad SU, Penta K, Yang W, Hallam TJ, Thanos CD, Sato AK. Zimmerman ES, et al. Among authors: hallam tj. Bioconjug Chem. 2014 Feb 19;25(2):351-61. doi: 10.1021/bc400490z. Epub 2014 Jan 29. Bioconjug Chem. 2014. PMID: 24437342
Methods to Make Homogenous Antibody Drug Conjugates.
Kline T, Steiner AR, Penta K, Sato AK, Hallam TJ, Yin G. Kline T, et al. Among authors: hallam tj. Pharm Res. 2015 Nov;32(11):3480-93. doi: 10.1007/s11095-014-1596-8. Epub 2014 Dec 16. Pharm Res. 2015. PMID: 25511917 Free PMC article. Review.
RF1 attenuation enables efficient non-natural amino acid incorporation for production of homogeneous antibody drug conjugates.
Yin G, Stephenson HT, Yang J, Li X, Armstrong SM, Heibeck TH, Tran C, Masikat MR, Zhou S, Stafford RL, Yam AY, Lee J, Steiner AR, Gill A, Penta K, Pollitt S, Baliga R, Murray CJ, Thanos CD, McEvoy LM, Sato AK, Hallam TJ. Yin G, et al. Among authors: hallam tj. Sci Rep. 2017 Jun 8;7(1):3026. doi: 10.1038/s41598-017-03192-z. Sci Rep. 2017. PMID: 28596531 Free PMC article.
Post-Exposure Protection in Mice against Sudan Virus by a Two Antibody Cocktail.
Froude JW, Herbert AS, Pelat T, Miethe S, Zak SE, Brannan JM, Bakken RR, Steiner AR, Yin G, Hallam TJ, Sato AK, Hust M, Thullier P, Dye JM. Froude JW, et al. Among authors: hallam tj. Viruses. 2018 May 26;10(6):286. doi: 10.3390/v10060286. Viruses. 2018. PMID: 29861435 Free PMC article.
Development of an E. coli strain for cell-free ADC manufacturing.
Groff D, Carlos NA, Chen R, Hanson JA, Liang S, Armstrong S, Li X, Zhou S, Steiner A, Hallam TJ, Yin G. Groff D, et al. Among authors: hallam tj. Biotechnol Bioeng. 2022 Jan;119(1):162-175. doi: 10.1002/bit.27961. Epub 2021 Oct 25. Biotechnol Bioeng. 2022. PMID: 34655229 Free PMC article.
Cell-free technologies for biopharmaceutical research and production.
Zawada JF, Burgenson D, Yin G, Hallam TJ, Swartz JR, Kiss RD. Zawada JF, et al. Among authors: hallam tj. Curr Opin Biotechnol. 2022 Aug;76:102719. doi: 10.1016/j.copbio.2022.102719. Epub 2022 May 12. Curr Opin Biotechnol. 2022. PMID: 35569340 Review.
71 results