Castañeda CA - Search Results

1

Mechanistic insights into enhancement or inhibition of phase separation by different polyubiquitin chains.

Dao TP, Yang Y, Presti MF, Cosgrove MS, Hopkins JB, Ma W, Loh SN, Castañeda CA. Dao TP, et al. Among authors: castaneda ca. EMBO Rep. 2022 Aug 3;23(8):e55056. doi: 10.15252/embr.202255056. Epub 2022 Jun 28. EMBO Rep. 2022. PMID: 35762418 Free PMC article.

2

Linkage-specific conformational ensembles of non-canonical polyubiquitin chains.

Castañeda CA, Chaturvedi A, Camara CM, Curtis JE, Krueger S, Fushman D. Castañeda CA, et al. Phys Chem Chem Phys. 2016 Feb 17;18(8):5771-88. doi: 10.1039/c5cp04601g. Phys Chem Chem Phys. 2016. PMID: 26422168 Free PMC article.

3

Engineered Domain Swapping as an On/Off Switch for Protein Function.

Ha JH, Karchin JM, Walker-Kopp N, Castañeda CA, Loh SN. Ha JH, et al. Among authors: castaneda ca. Chem Biol. 2015 Oct 22;22(10):1384-93. doi: 10.1016/j.chembiol.2015.09.007. Chem Biol. 2015. PMID: 26496687 Free PMC article.

4

Ubiquitin Modulates Liquid-Liquid Phase Separation of UBQLN2 via Disruption of Multivalent Interactions.

Dao TP, Kolaitis RM, Kim HJ, O'Donovan K, Martyniak B, Colicino E, Hehnly H, Taylor JP, Castañeda CA. Dao TP, et al. Among authors: castaneda ca. Mol Cell. 2018 Mar 15;69(6):965-978.e6. doi: 10.1016/j.molcel.2018.02.004. Epub 2018 Mar 8. Mol Cell. 2018. PMID: 29526694 Free PMC article.

5

Cancer Mutations in SPOP Put a Stop to Its Inter-compartmental Hops.

Riley JF, Dao TP, Castañeda CA. Riley JF, et al. Among authors: castaneda ca. Mol Cell. 2018 Oct 4;72(1):1-3. doi: 10.1016/j.molcel.2018.09.025. Mol Cell. 2018. PMID: 30290146 Free article.

6

Single Amino Acid Substitutions in Stickers, but Not Spacers, Substantially Alter UBQLN2 Phase Transitions and Dense Phase Material Properties.

Yang Y, Jones HB, Dao TP, Castañeda CA. Yang Y, et al. Among authors: castaneda ca. J Phys Chem B. 2019 May 2;123(17):3618-3629. doi: 10.1021/acs.jpcb.9b01024. Epub 2019 Apr 19. J Phys Chem B. 2019. PMID: 30925840

7

ALS-Linked Mutations Affect UBQLN2 Oligomerization and Phase Separation in a Position- and Amino Acid-Dependent Manner.

Dao TP, Martyniak B, Canning AJ, Lei Y, Colicino EG, Cosgrove MS, Hehnly H, Castañeda CA. Dao TP, et al. Among authors: castaneda ca. Structure. 2019 Jun 4;27(6):937-951.e5. doi: 10.1016/j.str.2019.03.012. Epub 2019 Apr 11. Structure. 2019. PMID: 30982635 Free PMC article.

8

Ubiquitin-Modulated Phase Separation of Shuttle Proteins: Does Condensate Formation Promote Protein Degradation?

Dao TP, Castañeda CA. Dao TP, et al. Among authors: castaneda ca. Bioessays. 2020 Nov;42(11):e2000036. doi: 10.1002/bies.202000036. Epub 2020 Sep 3. Bioessays. 2020. PMID: 32881044 Free PMC article. Review.

9

Structure, dynamics and functions of UBQLNs: at the crossroads of protein quality control machinery.

Zheng T, Yang Y, Castañeda CA. Zheng T, et al. Among authors: castaneda ca. Biochem J. 2020 Sep 30;477(18):3471-3497. doi: 10.1042/BCJ20190497. Biochem J. 2020. PMID: 32965492 Free PMC article. Review.

10

Structure analysis suggests Ess1 isomerizes the carboxy-terminal domain of RNA polymerase II via a bivalent anchoring mechanism.

Namitz KEW, Zheng T, Canning AJ, Alicea-Velazquez NL, Castañeda CA, Cosgrove MS, Hanes SD. Namitz KEW, et al. Among authors: castaneda ca. Commun Biol. 2021 Mar 25;4(1):398. doi: 10.1038/s42003-021-01906-8. Commun Biol. 2021. PMID: 33767358 Free PMC article.

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