Leonard A - Search Results

1

Gene Therapy for Hemoglobinopathies: Beta-Thalassemia, Sickle Cell Disease.

Leonard A, Tisdale JF, Bonner M. Leonard A, et al. Hematol Oncol Clin North Am. 2022 Aug;36(4):769-795. doi: 10.1016/j.hoc.2022.03.008. Epub 2022 Jun 27. Hematol Oncol Clin North Am. 2022. PMID: 35773052 Review.

2

Stem cell transplantation in sickle cell disease: therapeutic potential and challenges faced.

Leonard A, Tisdale JF. Leonard A, et al. Expert Rev Hematol. 2018 Jul;11(7):547-565. doi: 10.1080/17474086.2018.1486703. Epub 2018 Jun 20. Expert Rev Hematol. 2018. PMID: 29883237 Free PMC article. Review.

3

CRISPR/Cas9 for Sickle Cell Disease: Applications, Future Possibilities, and Challenges.

Demirci S, Leonard A, Haro-Mora JJ, Uchida N, Tisdale JF. Demirci S, et al. Among authors: leonard a. Adv Exp Med Biol. 2019;1144:37-52. doi: 10.1007/5584_2018_331. Adv Exp Med Biol. 2019. PMID: 30715679 Review.

4

High-Efficiency Lentiviral Transduction of Human CD34⁺ Cells in High-Density Culture with Poloxamer and Prostaglandin E2.

Uchida N, Nassehi T, Drysdale CM, Gamer J, Yapundich M, Demirci S, Haro-Mora JJ, Leonard A, Hsieh MM, Tisdale JF. Uchida N, et al. Among authors: leonard a. Mol Ther Methods Clin Dev. 2019 Jan 25;13:187-196. doi: 10.1016/j.omtm.2019.01.005. eCollection 2019 Jun 14. Mol Ther Methods Clin Dev. 2019. PMID: 30788387 Free PMC article.

5

Bone marrow characterization in sickle cell disease: inflammation and stress erythropoiesis lead to suboptimal CD34 recovery.

Leonard A, Bonifacino A, Dominical VM, Luo M, Haro-Mora JJ, Demirci S, Uchida N, Pierciey FJ Jr, Tisdale JF. Leonard A, et al. Br J Haematol. 2019 Jul;186(2):286-299. doi: 10.1111/bjh.15902. Epub 2019 Apr 10. Br J Haematol. 2019. PMID: 30972754 Free PMC article.

6

Low-Dose Busulfan Reduces Human CD34⁺ Cell Doses Required for Engraftment in c-kit Mutant Immunodeficient Mice.

Leonard A, Yapundich M, Nassehi T, Gamer J, Drysdale CM, Haro-Mora JJ, Demirci S, Hsieh MM, Uchida N, Tisdale JF. Leonard A, et al. Mol Ther Methods Clin Dev. 2019 Nov 11;15:430-437. doi: 10.1016/j.omtm.2019.10.017. eCollection 2019 Dec 13. Mol Ther Methods Clin Dev. 2019. PMID: 31890735 Free PMC article.

7

Curative options for sickle cell disease: haploidentical stem cell transplantation or gene therapy?

Leonard A, Tisdale J, Abraham A. Leonard A, et al. Br J Haematol. 2020 May;189(3):408-423. doi: 10.1111/bjh.16437. Epub 2020 Feb 7. Br J Haematol. 2020. PMID: 32034776 Free article. Review.

8

[No title available]

[No authors listed] [No authors listed] PMID: 32054658

9

Genome editing strategies for fetal hemoglobin induction in beta-hemoglobinopathies.

Demirci S, Leonard A, Tisdale JF. Demirci S, et al. Among authors: leonard a. Hum Mol Genet. 2020 Sep 30;29(R1):R100-R106. doi: 10.1093/hmg/ddaa088. Hum Mol Genet. 2020. PMID: 32406490 Free PMC article. Review.

10

Hematopoietic stem cells from pluripotent stem cells: Clinical potential, challenges, and future perspectives.

Demirci S, Leonard A, Tisdale JF. Demirci S, et al. Among authors: leonard a. Stem Cells Transl Med. 2020 Dec;9(12):1549-1557. doi: 10.1002/sctm.20-0247. Epub 2020 Jul 29. Stem Cells Transl Med. 2020. PMID: 32725882 Free PMC article. Review.

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