Pozzi N - Search Results

1

Reduction of protein disulfide isomerase results in open conformations and stimulates dynamic exchange between structural ensembles.

Chinnaraj M, Flaumenhaft R, Pozzi N. Chinnaraj M, et al. Among authors: pozzi n. J Biol Chem. 2022 Aug;298(8):102217. doi: 10.1016/j.jbc.2022.102217. Epub 2022 Jun 30. J Biol Chem. 2022. PMID: 35780832 Free PMC article.

2

Autoactivation of thrombin precursors.

Pozzi N, Chen Z, Zapata F, Niu W, Barranco-Medina S, Pelc LA, Di Cera E. Pozzi N, et al. J Biol Chem. 2013 Apr 19;288(16):11601-10. doi: 10.1074/jbc.M113.451542. Epub 2013 Mar 6. J Biol Chem. 2013. PMID: 23467412 Free PMC article.

3

Crystal structure of prothrombin reveals conformational flexibility and mechanism of activation.

Pozzi N, Chen Z, Gohara DW, Niu W, Heyduk T, Di Cera E. Pozzi N, et al. J Biol Chem. 2013 Aug 2;288(31):22734-44. doi: 10.1074/jbc.M113.466946. Epub 2013 Jun 17. J Biol Chem. 2013. PMID: 23775088 Free PMC article.

4

Histone H4 promotes prothrombin autoactivation.

Barranco-Medina S, Pozzi N, Vogt AD, Di Cera E. Barranco-Medina S, et al. Among authors: pozzi n. J Biol Chem. 2013 Dec 13;288(50):35749-57. doi: 10.1074/jbc.M113.509786. Epub 2013 Oct 30. J Biol Chem. 2013. PMID: 24178300 Free PMC article.

5

How the Linker Connecting the Two Kringles Influences Activation and Conformational Plasticity of Prothrombin.

Pozzi N, Chen Z, Di Cera E. Pozzi N, et al. J Biol Chem. 2016 Mar 18;291(12):6071-82. doi: 10.1074/jbc.M115.700401. Epub 2016 Jan 12. J Biol Chem. 2016. PMID: 26763231 Free PMC article.

6

Structural Architecture of Prothrombin in Solution Revealed by Single Molecule Spectroscopy.

Pozzi N, Bystranowska D, Zuo X, Di Cera E. Pozzi N, et al. J Biol Chem. 2016 Aug 26;291(35):18107-16. doi: 10.1074/jbc.M116.738310. Epub 2016 Jul 19. J Biol Chem. 2016. PMID: 27435675 Free PMC article.

7

Structure of prothrombin in the closed form reveals new details on the mechanism of activation.

Chinnaraj M, Chen Z, Pelc LA, Grese Z, Bystranowska D, Di Cera E, Pozzi N. Chinnaraj M, et al. Among authors: pozzi n. Sci Rep. 2018 Feb 13;8(1):2945. doi: 10.1038/s41598-018-21304-1. Sci Rep. 2018. PMID: 29440720 Free PMC article.

8

Structure of Coagulation Factor II: Molecular Mechanism of Thrombin Generation and Development of Next-Generation Anticoagulants.

Chinnaraj M, Planer W, Pozzi N. Chinnaraj M, et al. Among authors: pozzi n. Front Med (Lausanne). 2018 Oct 2;5:281. doi: 10.3389/fmed.2018.00281. eCollection 2018. Front Med (Lausanne). 2018. PMID: 30333979 Free PMC article. Review.

9

Discovery and characterization of 2 novel subpopulations of aPS/PT antibodies in patients at high risk of thrombosis.

Chinnaraj M, Planer W, Pengo V, Pozzi N. Chinnaraj M, et al. Among authors: pozzi n. Blood Adv. 2019 Jun 11;3(11):1738-1749. doi: 10.1182/bloodadvances.2019030932. Blood Adv. 2019. PMID: 31175129 Free PMC article.

10

The J-elongated conformation of β₂-glycoprotein I predominates in solution: implications for our understanding of antiphospholipid syndrome.

Ruben E, Planer W, Chinnaraj M, Chen Z, Zuo X, Pengo V, De Filippis V, Alluri RK, McCrae KR, Macor P, Tedesco F, Pozzi N. Ruben E, et al. Among authors: pozzi n. J Biol Chem. 2020 Jul 31;295(31):10794-10806. doi: 10.1074/jbc.RA120.013939. Epub 2020 Jun 9. J Biol Chem. 2020. PMID: 32518155 Free PMC article.

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