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Page 1
Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
Axelsson Raja A, Wakimoto H, DeLaughter DM, Reichart D, Gorham J, Conner DA, Lun M, Probst CK, Sakai N, Knipe RS, Montesi SB, Shea B, Adam LP, Leinwand LA, Wan W, Choi ES, Lindberg EL, Patone G, Noseda M, Hübner N, Seidman CE, Tager AM, Seidman JG, Ho CY. Axelsson Raja A, et al. Among authors: wakimoto h. Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2204174119. doi: 10.1073/pnas.2204174119. Epub 2022 Jul 5. Proc Natl Acad Sci U S A. 2022. PMID: 35787042 Free PMC article.
Comparison of two murine models of familial hypertrophic cardiomyopathy.
McConnell BK, Fatkin D, Semsarian C, Jones KA, Georgakopoulos D, Maguire CT, Healey MJ, Mudd JO, Moskowitz IP, Conner DA, Giewat M, Wakimoto H, Berul CI, Schoen FJ, Kass DA, Seidman CE, Seidman JG. McConnell BK, et al. Among authors: wakimoto h. Circ Res. 2001 Mar 2;88(4):383-9. doi: 10.1161/01.res.88.4.383. Circ Res. 2001. PMID: 11230104
A mouse model of congenital heart disease: cardiac arrhythmias and atrial septal defect caused by haploinsufficiency of the cardiac transcription factor Csx/Nkx2.5.
Tanaka M, Berul CI, Ishii M, Jay PY, Wakimoto H, Douglas P, Yamasaki N, Kawamoto T, Gehrmann J, Maguire CT, Schinke M, Seidman CE, Seidman JG, Kurachi Y, Izumo S. Tanaka M, et al. Among authors: wakimoto h. Cold Spring Harb Symp Quant Biol. 2002;67:317-25. doi: 10.1101/sqb.2002.67.317. Cold Spring Harb Symp Quant Biol. 2002. PMID: 12858555 No abstract available.
Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.
Wolf CM, Wang L, Alcalai R, Pizard A, Burgon PG, Ahmad F, Sherwood M, Branco DM, Wakimoto H, Fishman GI, See V, Stewart CL, Conner DA, Berul CI, Seidman CE, Seidman JG. Wolf CM, et al. Among authors: wakimoto h. J Mol Cell Cardiol. 2008 Feb;44(2):293-303. doi: 10.1016/j.yjmcc.2007.11.008. Epub 2007 Dec 3. J Mol Cell Cardiol. 2008. PMID: 18182166 Free PMC article.
Dissecting spatio-temporal protein networks driving human heart development and related disorders.
Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham JM, Workman CT, Bendsen E, Hansen NT, Rigina O, Roque FS, Wiese C, Christoffels VM, Roberts AE, Smoot LB, Pu WT, Donahoe PK, Tommerup N, Brunak S, Seidman CE, Seidman JG, Larsen LA. Lage K, et al. Among authors: wakimoto h. Mol Syst Biol. 2010 Jun 22;6:381. doi: 10.1038/msb.2010.36. Mol Syst Biol. 2010. PMID: 20571530 Free PMC article.
Prevention of ventricular arrhythmia and calcium dysregulation in a catecholaminergic polymorphic ventricular tachycardia mouse model carrying calsequestrin-2 mutation.
Alcalai R, Wakimoto H, Arad M, Planer D, Konno T, Wang L, Seidman JG, Seidman CE, Berul CI. Alcalai R, et al. Among authors: wakimoto h. J Cardiovasc Electrophysiol. 2011 Mar;22(3):316-24. doi: 10.1111/j.1540-8167.2010.01877.x. Epub 2010 Aug 30. J Cardiovasc Electrophysiol. 2011. PMID: 20807279 Free PMC article.
Cardiac fibrosis in mice with hypertrophic cardiomyopathy is mediated by non-myocyte proliferation and requires Tgf-β.
Teekakirikul P, Eminaga S, Toka O, Alcalai R, Wang L, Wakimoto H, Nayor M, Konno T, Gorham JM, Wolf CM, Kim JB, Schmitt JP, Molkentin JD, Norris RA, Tager AM, Hoffman SR, Markwald RR, Seidman CE, Seidman JG. Teekakirikul P, et al. Among authors: wakimoto h. J Clin Invest. 2010 Oct;120(10):3520-9. doi: 10.1172/JCI42028. Epub 2010 Sep 1. J Clin Invest. 2010. PMID: 20811150 Free PMC article.
317 results