Jackson SE - Search Results

1

Mechanistic insights into the rational design of masked antibodies.

Orozco CT, Bersellini M, Irving LM, Howard WW, Hargreaves D, Devine PWA, Siouve E, Browne GJ, Bond NJ, Phillips JJ, Ravn P, Jackson SE. Orozco CT, et al. Among authors: jackson se. MAbs. 2022 Jan-Dec;14(1):2095701. doi: 10.1080/19420862.2022.2095701. MAbs. 2022. PMID: 35799328 Free PMC article.

2

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs.

Phillips JJ, Yao ZP, Zhang W, McLaughlin S, Laue ED, Robinson CV, Jackson SE. Phillips JJ, et al. Among authors: jackson se. J Mol Biol. 2007 Oct 5;372(5):1189-203. doi: 10.1016/j.jmb.2007.04.059. Epub 2007 Apr 27. J Mol Biol. 2007. PMID: 17764690

3

Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation.

Orozco CT, Edgeworth MJ, Devine PWA, Hines AR, Cornwell O, Thompson C, Wang X, Phillips JJ, Ravn P, Jackson SE, Bond NJ. Orozco CT, et al. Among authors: jackson se. Bioconjug Chem. 2021 Aug 18;32(8):1834-1844. doi: 10.1021/acs.bioconjchem.1c00286. Epub 2021 Aug 9. Bioconjug Chem. 2021. PMID: 34369158 Free article.

4

All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading.

Dannheim FM, Walsh SJ, Orozco CT, Hansen AH, Bargh JD, Jackson SE, Bond NJ, Parker JS, Carroll JS, Spring DR. Dannheim FM, et al. Among authors: jackson se. Chem Sci. 2022 Jul 20;13(30):8781-8790. doi: 10.1039/d2sc02198f. eCollection 2022 Aug 4. Chem Sci. 2022. PMID: 35975158 Free PMC article.

5

De novo design of knotted tandem repeat proteins.

Doyle LA, Takushi B, Kibler RD, Milles LF, Orozco CT, Jones JD, Jackson SE, Stoddard BL, Bradley P. Doyle LA, et al. Among authors: jackson se. Nat Commun. 2023 Oct 24;14(1):6746. doi: 10.1038/s41467-023-42388-y. Nat Commun. 2023. PMID: 37875492 Free PMC article.

6

Mechanistic studies on Hsp90 inhibition by ansamycin derivatives.

Onuoha SC, Mukund SR, Coulstock ET, Sengerovà B, Shaw J, McLaughlin SH, Jackson SE. Onuoha SC, et al. Among authors: jackson se. J Mol Biol. 2007 Sep 14;372(2):287-97. doi: 10.1016/j.jmb.2007.06.065. Epub 2007 Jun 29. J Mol Biol. 2007. PMID: 17662999

7

Context-dependent nature of destabilizing mutations on the stability of FKBP12.

Main ER, Fulton KF, Jackson SE. Main ER, et al. Among authors: jackson se. Biochemistry. 1998 Apr 28;37(17):6145-53. doi: 10.1021/bi973111s. Biochemistry. 1998. PMID: 9558354

8

Stimulation of the weak ATPase activity of human hsp90 by a client protein.

McLaughlin SH, Smith HW, Jackson SE. McLaughlin SH, et al. Among authors: jackson se. J Mol Biol. 2002 Jan 25;315(4):787-98. doi: 10.1006/jmbi.2001.5245. J Mol Biol. 2002. PMID: 11812147

9

Folding pathway of FKBP12 and characterisation of the transition state.

Main ER, Fulton KF, Jackson SE. Main ER, et al. Among authors: jackson se. J Mol Biol. 1999 Aug 13;291(2):429-44. doi: 10.1006/jmbi.1999.2941. J Mol Biol. 1999. PMID: 10438630

10

Toward Rapid Aspartic Acid Isomer Localization in Therapeutic Peptides Using Cyclic Ion Mobility Mass Spectrometry.

Gibson K, Cooper-Shepherd DA, Pallister E, Inman SE, Jackson SE, Lindo V. Gibson K, et al. Among authors: jackson se. J Am Soc Mass Spectrom. 2022 Jul 6;33(7):1204-1212. doi: 10.1021/jasms.2c00053. Epub 2022 May 24. J Am Soc Mass Spectrom. 2022. PMID: 35609180 Free PMC article.

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