Menyhárd DK - Search Results

1

Cryo-EM structure of acylpeptide hydrolase reveals substrate selection by multimerization and a multi-state serine-protease triad.

Kiss-Szemán AJ, Stráner P, Jákli I, Hosogi N, Harmat V, Menyhárd DK, Perczel A. Kiss-Szemán AJ, et al. Among authors: menyhard dk. Chem Sci. 2022 May 18;13(24):7132-7142. doi: 10.1039/d2sc02276a. eCollection 2022 Jun 22. Chem Sci. 2022. PMID: 35799812 Free PMC article.

2

Structure and catalysis of acylaminoacyl peptidase: closed and open subunits of a dimer oligopeptidase.

Harmat V, Domokos K, Menyhárd DK, Palló A, Szeltner Z, Szamosi I, Beke-Somfai T, Náray-Szabó G, Polgár L. Harmat V, et al. Among authors: menyhard dk. J Biol Chem. 2011 Jan 21;286(3):1987-98. doi: 10.1074/jbc.M110.169862. Epub 2010 Nov 16. J Biol Chem. 2011. PMID: 21084296 Free PMC article.

3

A self-compartmentalizing hexamer serine protease from Pyrococcus horikoshii: substrate selection achieved through multimerization.

Menyhárd DK, Kiss-Szemán A, Tichy-Rács É, Hornung B, Rádi K, Szeltner Z, Domokos K, Szamosi I, Náray-Szabó G, Polgár L, Harmat V. Menyhárd DK, et al. J Biol Chem. 2013 Jun 14;288(24):17884-94. doi: 10.1074/jbc.M113.451534. Epub 2013 Apr 30. J Biol Chem. 2013. PMID: 23632025 Free PMC article.

4

Mutation-dependent recessive inheritance of NPHS2-associated steroid-resistant nephrotic syndrome.

Tory K, Menyhárd DK, Woerner S, Nevo F, Gribouval O, Kerti A, Stráner P, Arrondel C, Huynh Cong E, Tulassay T, Mollet G, Perczel A, Antignac C. Tory K, et al. Among authors: menyhard dk. Nat Genet. 2014 Mar;46(3):299-304. doi: 10.1038/ng.2898. Epub 2014 Feb 9. Nat Genet. 2014. PMID: 24509478 Free article.

5

Phosphorylation as conformational switch from the native to amyloid state: Trp-cage as a protein aggregation model.

Kardos J, Kiss B, Micsonai A, Rovó P, Menyhárd DK, Kovács J, Váradi G, Tóth GK, Perczel A. Kardos J, et al. Among authors: menyhard dk. J Phys Chem B. 2015 Feb 19;119(7):2946-55. doi: 10.1021/jp5124234. Epub 2015 Feb 6. J Phys Chem B. 2015. PMID: 25625571

6

Catalytically distinct states captured in a crystal lattice: the substrate-bound and scavenger states of acylaminoacyl peptidase and their implications for functionality.

Menyhárd DK, Orgován Z, Szeltner Z, Szamosi I, Harmat V. Menyhárd DK, et al. Acta Crystallogr D Biol Crystallogr. 2015 Mar;71(Pt 3):461-72. doi: 10.1107/S1399004714026819. Epub 2015 Feb 26. Acta Crystallogr D Biol Crystallogr. 2015. PMID: 25760596 Free article.

7

Predictable Conformational Diversity in Foldamers of Sugar Amino Acids.

Menyhárd DK, Hudáky I, Jákli I, Juhász G, Perczel A. Menyhárd DK, et al. J Chem Inf Model. 2017 Apr 24;57(4):757-768. doi: 10.1021/acs.jcim.6b00488. Epub 2017 Apr 11. J Chem Inf Model. 2017. PMID: 28345931 Free article.

8

Hydration shell differentiates folded and disordered states of a Trp-cage miniprotein, allowing characterization of structural heterogeneity by wide-line NMR measurements.

Taricska N, Bokor M, Menyhárd DK, Tompa K, Perczel A. Taricska N, et al. Among authors: menyhard dk. Sci Rep. 2019 Feb 27;9(1):2947. doi: 10.1038/s41598-019-39121-5. Sci Rep. 2019. PMID: 30814556 Free PMC article.

9

Assignment of Vibrational Circular Dichroism Cross-Referenced Electronic Circular Dichroism Spectra of Flexible Foldamer Building Blocks: Towards Assigning Pure Chiroptical Properties of Foldamers.

Farkas V, Nagy A, Menyhárd DK, Perczel A. Farkas V, et al. Among authors: menyhard dk. Chemistry. 2019 Nov 22;25(65):14890-14900. doi: 10.1002/chem.201903023. Epub 2019 Oct 23. Chemistry. 2019. PMID: 31464009 Free PMC article.

10

Protein Aggregation in a Nutshell: The Splendid Molecular Architecture of the Dreaded Amyloid Fibrils.

Horváth D, Menyhárd DK, Perczel A. Horváth D, et al. Among authors: menyhard dk. Curr Protein Pept Sci. 2019;20(11):1077-1088. doi: 10.2174/1389203720666190925102832. Curr Protein Pept Sci. 2019. PMID: 31553291 Review.

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