Nair SJ - Search Results

1

Transcriptional enhancers at 40: evolution of a viral DNA element to nuclear architectural structures.

Nair SJ, Suter T, Wang S, Yang L, Yang F, Rosenfeld MG. Nair SJ, et al. Trends Genet. 2022 Oct;38(10):1019-1047. doi: 10.1016/j.tig.2022.05.015. Epub 2022 Jul 7. Trends Genet. 2022. PMID: 35811173 Free PMC article. Review.

2

Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly.

Nair SJ, Yang L, Meluzzi D, Oh S, Yang F, Friedman MJ, Wang S, Suter T, Alshareedah I, Gamliel A, Ma Q, Zhang J, Hu Y, Tan Y, Ohgi KA, Jayani RS, Banerjee PR, Aggarwal AK, Rosenfeld MG. Nair SJ, et al. Nat Struct Mol Biol. 2019 Mar;26(3):193-203. doi: 10.1038/s41594-019-0190-5. Epub 2019 Mar 4. Nat Struct Mol Biol. 2019. PMID: 30833784 Free PMC article.

3

Super-Enhancer Redistribution as a Mechanism of Broad Gene Dysregulation in Repeatedly Drug-Treated Cancer Cells.

Ma Q, Yang F, Mackintosh C, Jayani RS, Oh S, Jin C, Nair SJ, Merkurjev D, Ma W, Allen S, Wang D, Almenar-Queralt A, Garcia-Bassets I. Ma Q, et al. Among authors: nair sj. Cell Rep. 2020 Apr 21;31(3):107532. doi: 10.1016/j.celrep.2020.107532. Cell Rep. 2020. PMID: 32320655 Free article.

4

Enhancer release and retargeting activates disease-susceptibility genes.

Oh S, Shao J, Mitra J, Xiong F, D'Antonio M, Wang R, Garcia-Bassets I, Ma Q, Zhu X, Lee JH, Nair SJ, Yang F, Ohgi K, Frazer KA, Zhang ZD, Li W, Rosenfeld MG. Oh S, et al. Among authors: nair sj. Nature. 2021 Jul;595(7869):735-740. doi: 10.1038/s41586-021-03577-1. Epub 2021 May 26. Nature. 2021. PMID: 34040254 Free PMC article.

5

Long-distance association of topological boundaries through nuclear condensates.

Gamliel A, Meluzzi D, Oh S, Jiang N, Destici E, Rosenfeld MG, Nair SJ. Gamliel A, et al. Among authors: nair sj. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2206216119. doi: 10.1073/pnas.2206216119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914133 Free PMC article.

6

Signal-induced enhancer activation requires Ku70 to read topoisomerase1-DNA covalent complexes.

Tan Y, Yao L, Gamliel A, Nair SJ, Taylor H, Ohgi K, Aggarwal AK, Rosenfeld MG. Tan Y, et al. Among authors: nair sj. Nat Struct Mol Biol. 2023 Feb;30(2):148-158. doi: 10.1038/s41594-022-00883-8. Epub 2023 Feb 6. Nat Struct Mol Biol. 2023. PMID: 36747093 Free PMC article.

7

Genetic suppression reveals DNA repair-independent antagonism between BRCA1 and COBRA1 in mammary gland development.

Nair SJ, Zhang X, Chiang HC, Jahid MJ, Wang Y, Garza P, April C, Salathia N, Banerjee T, Alenazi FS, Ruan J, Fan JB, Parvin JD, Jin VX, Hu Y, Li R. Nair SJ, et al. Nat Commun. 2016 Mar 4;7:10913. doi: 10.1038/ncomms10913. Nat Commun. 2016. PMID: 26941120 Free PMC article.

8

Genetic and genomic analyses of RNA polymerase II-pausing factor in regulation of mammalian transcription and cell growth.

Sun J, Pan H, Lei C, Yuan B, Nair SJ, April C, Parameswaran B, Klotzle B, Fan JB, Ruan J, Li R. Sun J, et al. Among authors: nair sj. J Biol Chem. 2011 Oct 21;286(42):36248-57. doi: 10.1074/jbc.M111.269167. Epub 2011 Aug 24. J Biol Chem. 2011. PMID: 21865163 Free PMC article.

9

Attenuation of RNA polymerase II pausing mitigates BRCA1-associated R-loop accumulation and tumorigenesis.

Zhang X, Chiang HC, Wang Y, Zhang C, Smith S, Zhao X, Nair SJ, Michalek J, Jatoi I, Lautner M, Oliver B, Wang H, Petit A, Soler T, Brunet J, Mateo F, Angel Pujana M, Poggi E, Chaldekas K, Isaacs C, Peshkin BN, Ochoa O, Chedin F, Theoharis C, Sun LZ, Curiel TJ, Elledge R, Jin VX, Hu Y, Li R. Zhang X, et al. Among authors: nair sj. Nat Commun. 2017 Jun 26;8:15908. doi: 10.1038/ncomms15908. Nat Commun. 2017. PMID: 28649985 Free PMC article.

10

Mouse cofactor of BRCA1 (Cobra1) is required for early embryogenesis.

Amleh A, Nair SJ, Sun J, Sutherland A, Hasty P, Li R. Amleh A, et al. Among authors: nair sj. PLoS One. 2009;4(4):e5034. doi: 10.1371/journal.pone.0005034. Epub 2009 Apr 2. PLoS One. 2009. PMID: 19340312 Free PMC article.

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