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Most Pathways Can Be Related to the Pathogenesis of Alzheimer's Disease.
Morgan SL, Naderi P, Koler K, Pita-Juarez Y, Prokopenko D, Vlachos IS, Tanzi RE, Bertram L, Hide WA. Morgan SL, et al. Among authors: koler k. Front Aging Neurosci. 2022 Jun 24;14:846902. doi: 10.3389/fnagi.2022.846902. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35813951 Free PMC article.
The Pathway Coexpression Network: Revealing pathway relationships.
Pita-Juárez Y, Altschuler G, Kariotis S, Wei W, Koler K, Green C, Tanzi RE, Hide W. Pita-Juárez Y, et al. Among authors: koler k. PLoS Comput Biol. 2018 Mar 19;14(3):e1006042. doi: 10.1371/journal.pcbi.1006042. eCollection 2018 Mar. PLoS Comput Biol. 2018. PMID: 29554099 Free PMC article.
GCH1 Deficiency Activates Brain Innate Immune Response and Impairs Tyrosine Hydroxylase Homeostasis.
Larbalestier H, Keatinge M, Watson L, White E, Gowda S, Wei W, Koler K, Semenova SA, Elkin AM, Rimmer N, Sweeney ST, Mazzolini J, Sieger D, Hide W, McDearmid J, Panula P, MacDonald RB, Bandmann O. Larbalestier H, et al. Among authors: koler k. J Neurosci. 2022 Jan 26;42(4):702-716. doi: 10.1523/JNEUROSCI.0653-21.2021. Epub 2021 Dec 7. J Neurosci. 2022. PMID: 34876467 Free PMC article.
Integrative pathway analysis across humans and 3D cellular models identifies the p38 MAPK-MK2 axis as a therapeutic target for Alzheimer's disease.
Naderi Yeganeh P, Kwak SS, Jorfi M, Koler K, Kalatturu T, von Maydell D, Liu Z, Guo K, Choi Y, Park J, Abarca N, Bakiasi G, Cetinbas M, Sadreyev R, Griciuc A, Quinti L, Choi SH, Xia W, Tanzi RE, Hide W, Kim DY. Naderi Yeganeh P, et al. Among authors: koler k. Neuron. 2024 Nov 25:S0896-6273(24)00800-6. doi: 10.1016/j.neuron.2024.10.029. Online ahead of print. Neuron. 2024. PMID: 39610246