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The conserved Tpk1 regulates non-homologous end joining double-strand break repair by phosphorylation of Nej1, a homolog of the human XLF.
Jessulat M, Amin S, Hooshyar M, Malty R, Moutaoufik MT, Zilocchi M, Istace Z, Phanse S, Aoki H, Omidi K, Burnside D, Samanfar B, Aly KA, Golshani A, Babu M. Jessulat M, et al. Among authors: istace z. Nucleic Acids Res. 2021 Aug 20;49(14):8145-8160. doi: 10.1093/nar/gkab585. Nucleic Acids Res. 2021. PMID: 34244791 Free PMC article.