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The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases.
Lou PH, Lucchinetti E, Zhang L, Affolter A, Schaub MC, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M. Lou PH, et al. PLoS One. 2014 Jan 30;9(1):e87205. doi: 10.1371/journal.pone.0087205. eCollection 2014. PLoS One. 2014. PMID: 24498043 Free PMC article.
TMX1 determines cancer cell metabolism as a thiol-based modulator of ER-mitochondria Ca2+ flux.
Raturi A, Gutiérrez T, Ortiz-Sandoval C, Ruangkittisakul A, Herrera-Cruz MS, Rockley JP, Gesson K, Ourdev D, Lou PH, Lucchinetti E, Tahbaz N, Zaugg M, Baksh S, Ballanyi K, Simmen T. Raturi A, et al. Among authors: lou ph. J Cell Biol. 2016 Aug 15;214(4):433-44. doi: 10.1083/jcb.201512077. Epub 2016 Aug 8. J Cell Biol. 2016. PMID: 27502484 Free PMC article.
27 results