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Allosteric modulation of GPCRs: From structural insights to in silico drug discovery.
Pharmacol Ther. 2022 Sep;237:108242. doi: 10.1016/j.pharmthera.2022.108242. Epub 2022 Jul 18.
Pharmacol Ther. 2022.
PMID: 35863587
Review.
The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites.
Hedderich JB, Persechino M, Becker K, Heydenreich FM, Gutermuth T, Bouvier M, Bünemann M, Kolb P.
Hedderich JB, et al.
Nat Commun. 2022 May 10;13(1):2567. doi: 10.1038/s41467-022-29609-6.
Nat Commun. 2022.
PMID: 35538063
Free PMC article.
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