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Keratinocyte-derived defensins activate neutrophil-specific receptors Mrgpra2a/b to prevent skin dysbiosis and bacterial infection.
Dong X, Limjunyawong N, Sypek EI, Wang G, Ortines RV, Youn C, Alphonse MP, Dikeman D, Wang Y, Lay M, Kothari R, Vasavda C, Pundir P, Goff L, Miller LS, Lu W, Garza LA, Kim BS, Archer NK, Dong X. Dong X, et al. Among authors: kothari r. Immunity. 2022 Sep 13;55(9):1645-1662.e7. doi: 10.1016/j.immuni.2022.06.021. Epub 2022 Jul 25. Immunity. 2022. PMID: 35882236 Free PMC article.
Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide.
Vasavda C, Kothari R, Malla AP, Tokhunts R, Lin A, Ji M, Ricco C, Xu R, Saavedra HG, Sbodio JI, Snowman AM, Albacarys L, Hester L, Sedlak TW, Paul BD, Snyder SH. Vasavda C, et al. Among authors: kothari r. Cell Chem Biol. 2019 Oct 17;26(10):1450-1460.e7. doi: 10.1016/j.chembiol.2019.07.006. Epub 2019 Jul 25. Cell Chem Biol. 2019. PMID: 31353321 Free PMC article.
Scratching the surface of itch receptors.
Kothari R, Dong X. Kothari R, et al. Trends Pharmacol Sci. 2022 Mar;43(3):168-170. doi: 10.1016/j.tips.2021.12.005. Epub 2022 Jan 14. Trends Pharmacol Sci. 2022. PMID: 35039148
Biliverdin reductase bridges focal adhesion kinase to Src to modulate synaptic signaling.
Vasavda C, Semenza ER, Liew J, Kothari R, Dhindsa RS, Shanmukha S, Lin A, Tokhunts R, Ricco C, Snowman AM, Albacarys L, Pastore F, Ripoli C, Grassi C, Barone E, Kornberg MD, Dong X, Paul BD, Snyder SH. Vasavda C, et al. Among authors: kothari r. Sci Signal. 2022 May 10;15(733):eabh3066. doi: 10.1126/scisignal.abh3066. Epub 2022 May 10. Sci Signal. 2022. PMID: 35536885 Free PMC article.
Identification of the NRF2 transcriptional network as a therapeutic target for trigeminal neuropathic pain.
Vasavda C, Xu R, Liew J, Kothari R, Dhindsa RS, Semenza ER, Paul BD, Green DP, Sabbagh MF, Shin JY, Yang W, Snowman AM, Albacarys LK, Moghekar A, Pardo-Villamizar CA, Luciano M, Huang J, Bettegowda C, Kwatra SG, Dong X, Lim M, Snyder SH. Vasavda C, et al. Among authors: kothari r. Sci Adv. 2022 Aug 5;8(31):eabo5633. doi: 10.1126/sciadv.abo5633. Epub 2022 Aug 3. Sci Adv. 2022. PMID: 35921423 Free PMC article.
Cerebral collateral flow state in acute ischemic stroke correlates with clinical functional outcomes in non-thrombectomy patients.
Shah S, Wood S, Logue L, Meyer J, Pikel K, Germroth M, Peethamber G, Kodumuri N, Lowe J, Kothari R, Rahman L, Venkatesh S, Sen S. Shah S, et al. Among authors: kothari r. J Stroke Cerebrovasc Dis. 2024 Dec 22:108211. doi: 10.1016/j.jstrokecerebrovasdis.2024.108211. Online ahead of print. J Stroke Cerebrovasc Dis. 2024. PMID: 39719205
442 results