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Ring Trial on Quantitative Assessment of Bile Acids Reveals a Method- and Analyte-Specific Accuracy and Reproducibility.
Haange SB, Till A, Bergh PO, Fauler G, Gigl M, Löfgren-Sandblom A, Schaap FG, Clavel T, Trautwein C, Fenske W, Kleigrewe K, Marschall HU, Olde Damink SWM, Moustafa T, von Bergen M, Rolle-Kampczyk U. Haange SB, et al. Among authors: moustafa t. Metabolites. 2022 Jun 23;12(7):583. doi: 10.3390/metabo12070583. Metabolites. 2022. PMID: 35888707 Free PMC article.
Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids.
Zollner G, Wagner M, Moustafa T, Fickert P, Silbert D, Gumhold J, Fuchsbichler A, Halilbasic E, Denk H, Marschall HU, Trauner M. Zollner G, et al. Among authors: moustafa t. Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G923-32. doi: 10.1152/ajpgi.00490.2005. Epub 2005 Dec 15. Am J Physiol Gastrointest Liver Physiol. 2006. PMID: 16357057 Free article.
A new xenobiotic-induced mouse model of sclerosing cholangitis and biliary fibrosis.
Fickert P, Stöger U, Fuchsbichler A, Moustafa T, Marschall HU, Weiglein AH, Tsybrovskyy O, Jaeschke H, Zatloukal K, Denk H, Trauner M. Fickert P, et al. Among authors: moustafa t. Am J Pathol. 2007 Aug;171(2):525-36. doi: 10.2353/ajpath.2007.061133. Epub 2007 Jun 28. Am J Pathol. 2007. PMID: 17600122 Free PMC article.
Side chain structure determines unique physiologic and therapeutic properties of norursodeoxycholic acid in Mdr2-/- mice.
Halilbasic E, Fiorotto R, Fickert P, Marschall HU, Moustafa T, Spirli C, Fuchsbichler A, Gumhold J, Silbert D, Zatloukal K, Langner C, Maitra U, Denk H, Hofmann AF, Strazzabosco M, Trauner M. Halilbasic E, et al. Among authors: moustafa t. Hepatology. 2009 Jun;49(6):1972-81. doi: 10.1002/hep.22891. Hepatology. 2009. PMID: 19475687 Free PMC article.
Alterations in lipid metabolism mediate inflammation, fibrosis, and proliferation in a mouse model of chronic cholestatic liver injury.
Moustafa T, Fickert P, Magnes C, Guelly C, Thueringer A, Frank S, Kratky D, Sattler W, Reicher H, Sinner F, Gumhold J, Silbert D, Fauler G, Höfler G, Lass A, Zechner R, Trauner M. Moustafa T, et al. Gastroenterology. 2012 Jan;142(1):140-151.e12. doi: 10.1053/j.gastro.2011.09.051. Epub 2011 Oct 14. Gastroenterology. 2012. PMID: 22001865
The gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice.
Streidl T, Karkossa I, Segura Muñoz RR, Eberl C, Zaufel A, Plagge J, Schmaltz R, Schubert K, Basic M, Schneider KM, Afify M, Trautwein C, Tolba R, Stecher B, Doden HL, Ridlon JM, Ecker J, Moustafa T, von Bergen M, Ramer-Tait AE, Clavel T. Streidl T, et al. Among authors: moustafa t. Gut Microbes. 2021 Jan-Dec;13(1):1-21. doi: 10.1080/19490976.2020.1854008. Gut Microbes. 2021. PMID: 33382950 Free PMC article.
Secondary (iso)BAs cooperate with endogenous ligands to activate FXR under physiological and pathological conditions.
Zaufel A, van de Wiel SMW, Yin L, Fauler G, Chien D, Dong X, Gilmer JF, Truong JK, Dawson PA, van de Graaf SFJ, Fickert P, Moustafa T. Zaufel A, et al. Among authors: moustafa t. Biochim Biophys Acta Mol Basis Dis. 2021 Aug 1;1867(8):166153. doi: 10.1016/j.bbadis.2021.166153. Epub 2021 Apr 22. Biochim Biophys Acta Mol Basis Dis. 2021. PMID: 33895309 Free PMC article.
Bile acids trigger cholemic nephropathy in common bile-duct-ligated mice.
Fickert P, Krones E, Pollheimer MJ, Thueringer A, Moustafa T, Silbert D, Halilbasic E, Yang M, Jaeschke H, Stokman G, Wells RG, Eller K, Rosenkranz AR, Eggertsen G, Wagner CA, Langner C, Denk H, Trauner M. Fickert P, et al. Among authors: moustafa t. Hepatology. 2013 Dec;58(6):2056-69. doi: 10.1002/hep.26599. Epub 2013 Oct 15. Hepatology. 2013. PMID: 23813550
62 results