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Page 1
Htt CAG repeat expansion confers pleiotropic gains of mutant huntingtin function in chromatin regulation.
Biagioli M, Ferrari F, Mendenhall EM, Zhang Y, Erdin S, Vijayvargia R, Vallabh SM, Solomos N, Manavalan P, Ragavendran A, Ozsolak F, Lee JM, Talkowski ME, Gusella JF, Macdonald ME, Park PJ, Seong IS. Biagioli M, et al. Among authors: vijayvargia r. Hum Mol Genet. 2015 May 1;24(9):2442-57. doi: 10.1093/hmg/ddv006. Epub 2015 Jan 8. Hum Mol Genet. 2015. PMID: 25574027 Free PMC article.
Novel DNA Aptamers that Bind to Mutant Huntingtin and Modify Its Activity.
Shin B, Jung R, Oh H, Owens GE, Lee H, Kwak S, Lee R, Cotman SL, Lee JM, MacDonald ME, Song JJ, Vijayvargia R, Seong IS. Shin B, et al. Among authors: vijayvargia r. Mol Ther Nucleic Acids. 2018 Jun 1;11:416-428. doi: 10.1016/j.omtn.2018.03.008. Epub 2018 Mar 16. Mol Ther Nucleic Acids. 2018. PMID: 29858077 Free PMC article.
The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain.
Jung T, Shin B, Tamo G, Kim H, Vijayvargia R, Leitner A, Marcaida MJ, Astorga-Wells J, Jung R, Aebersold R, Peraro MD, Hebert H, Seong IS, Song JJ. Jung T, et al. Among authors: vijayvargia r. Structure. 2020 Sep 1;28(9):1035-1050.e8. doi: 10.1016/j.str.2020.06.008. Epub 2020 Jul 14. Structure. 2020. PMID: 32668197 Free PMC article.
Post-Translational Modifications (PTMs), Identified on Endogenous Huntingtin, Cluster within Proteolytic Domains between HEAT Repeats.
Ratovitski T, O'Meally RN, Jiang M, Chaerkady R, Chighladze E, Stewart JC, Wang X, Arbez N, Roby E, Alexandris A, Duan W, Vijayvargia R, Seong IS, Lavery DJ, Cole RN, Ross CA. Ratovitski T, et al. Among authors: vijayvargia r. J Proteome Res. 2017 Aug 4;16(8):2692-2708. doi: 10.1021/acs.jproteome.6b00991. Epub 2017 Jul 3. J Proteome Res. 2017. PMID: 28653853 Free PMC article.
Hypomorphic mutation of the mouse Huntington's disease gene orthologue.
Murthy V, Tebaldi T, Yoshida T, Erdin S, Calzonetti T, Vijayvargia R, Tripathi T, Kerschbamer E, Seong IS, Quattrone A, Talkowski ME, Gusella JF, Georgopoulos K, MacDonald ME, Biagioli M. Murthy V, et al. Among authors: vijayvargia r. PLoS Genet. 2019 Mar 21;15(3):e1007765. doi: 10.1371/journal.pgen.1007765. eCollection 2019 Mar. PLoS Genet. 2019. PMID: 30897080 Free PMC article.
Nortriptyline-Induced Room Tilt Illusion.
Sarmiento BA, Varghese R, Vijayvargia R, Gunther M, Fusick A, Jiang S. Sarmiento BA, et al. Among authors: vijayvargia r. Cureus. 2024 Jan 11;16(1):e52101. doi: 10.7759/cureus.52101. eCollection 2024 Jan. Cureus. 2024. PMID: 38344625 Free PMC article.
Design, synthesis, biological evaluation and molecular dynamics of some novel 3-phenylpyrazolo[1,5-a]pyrimidine-2,7(1H,4H)-dione based compounds as anti-tubercular agents.
Chauhan M, Prajapati C, Mirza S, Barot R, Yadav R, Barmade M, Kakadiya D, Vijayvargia R, Haobam B, Baidya AT, Kumar R, Yadav MR, Murumkar P. Chauhan M, et al. Among authors: vijayvargia r. J Biomol Struct Dyn. 2024 Oct;42(17):9031-9049. doi: 10.1080/07391102.2023.2249109. Epub 2023 Sep 1. J Biomol Struct Dyn. 2024. PMID: 37655680
21 results