Zhang Z - Search Results

1

Germline Missense Variants in CDC20 Result in Aberrant Mitotic Progression and Familial Cancer.

Chen OJ, Castellsagué E, Moustafa-Kamal M, Nadaf J, Rivera B, Fahiminiya S, Wang Y, Gamache I, Pacifico C, Jiang L, Carrot-Zhang J, Witkowski L, Berghuis AM, Schönberger S, Schneider D, Hillmer M, Bens S, Siebert R, Stewart CJR, Zhang Z, Chao WCH, Greenwood CMT, Barford D, Tischkowitz M, Majewski J, Foulkes WD, Teodoro JG. Chen OJ, et al. Among authors: zhang z. Cancer Res. 2022 Oct 4;82(19):3499-3515. doi: 10.1158/0008-5472.CAN-21-3956. Cancer Res. 2022. PMID: 35913887

2

Molecular structure of the N-terminal domain of the APC/C subunit Cdc27 reveals a homo-dimeric tetratricopeptide repeat architecture.

Zhang Z, Roe SM, Diogon M, Kong E, El Alaoui H, Barford D. Zhang Z, et al. J Mol Biol. 2010 Apr 16;397(5):1316-28. doi: 10.1016/j.jmb.2010.02.045. Epub 2010 Mar 3. J Mol Biol. 2010. PMID: 20206185

3

The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27.

Zhang Z, Kulkarni K, Hanrahan SJ, Thompson AJ, Barford D. Zhang Z, et al. EMBO J. 2010 Nov 3;29(21):3733-44. doi: 10.1038/emboj.2010.247. Epub 2010 Oct 5. EMBO J. 2010. PMID: 20924356 Free PMC article.

4

Structures of APC/C(Cdh1) with substrates identify Cdh1 and Apc10 as the D-box co-receptor.

da Fonseca PC, Kong EH, Zhang Z, Schreiber A, Williams MA, Morris EP, Barford D. da Fonseca PC, et al. Among authors: zhang z. Nature. 2011 Feb 10;470(7333):274-8. doi: 10.1038/nature09625. Epub 2010 Nov 24. Nature. 2011. PMID: 21107322 Free PMC article.

5

Structural basis for the subunit assembly of the anaphase-promoting complex.

Schreiber A, Stengel F, Zhang Z, Enchev RI, Kong EH, Morris EP, Robinson CV, da Fonseca PC, Barford D. Schreiber A, et al. Among authors: zhang z. Nature. 2011 Feb 10;470(7333):227-32. doi: 10.1038/nature09756. Nature. 2011. PMID: 21307936

6

Multiple factors confer specific Cdc42 and Rac protein activation by dedicator of cytokinesis (DOCK) nucleotide exchange factors.

Kulkarni K, Yang J, Zhang Z, Barford D. Kulkarni K, et al. Among authors: zhang z. J Biol Chem. 2011 Jul 15;286(28):25341-51. doi: 10.1074/jbc.M111.236455. Epub 2011 May 24. J Biol Chem. 2011. PMID: 21613211 Free PMC article.

7

Structure of the mitotic checkpoint complex.

Chao WC, Kulkarni K, Zhang Z, Kong EH, Barford D. Chao WC, et al. Among authors: zhang z. Nature. 2012 Mar 21;484(7393):208-13. doi: 10.1038/nature10896. Nature. 2012. PMID: 22437499

8

Recombinant expression, reconstitution and structure of human anaphase-promoting complex (APC/C).

Zhang Z, Yang J, Kong EH, Chao WC, Morris EP, da Fonseca PC, Barford D. Zhang Z, et al. Biochem J. 2013 Jan 15;449(2):365-71. doi: 10.1042/BJ20121374. Biochem J. 2013. PMID: 23078409

9

The four canonical tpr subunits of human APC/C form related homo-dimeric structures and stack in parallel to form a TPR suprahelix.

Zhang Z, Chang L, Yang J, Conin N, Kulkarni K, Barford D. Zhang Z, et al. J Mol Biol. 2013 Nov 15;425(22):4236-48. doi: 10.1016/j.jmb.2013.04.004. Epub 2013 Apr 11. J Mol Biol. 2013. PMID: 23583778 Free PMC article.

10

Insights into degron recognition by APC/C coactivators from the structure of an Acm1-Cdh1 complex.

He J, Chao WC, Zhang Z, Yang J, Cronin N, Barford D. He J, et al. Among authors: zhang z. Mol Cell. 2013 Jun 6;50(5):649-60. doi: 10.1016/j.molcel.2013.04.024. Epub 2013 May 23. Mol Cell. 2013. PMID: 23707760 Free PMC article.

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