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Cell-penetrating peptides enhance peptide vaccine accumulation and persistence in lymph nodes to drive immunogenicity.
Backlund CM, Holden RL, Moynihan KD, Garafola D, Farquhar C, Mehta NK, Maiorino L, Pham S, Iorgulescu JB, Reardon DA, Wu CJ, Pentelute BL, Irvine DJ. Backlund CM, et al. Among authors: irvine dj. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2204078119. doi: 10.1073/pnas.2204078119. Epub 2022 Aug 1. Proc Natl Acad Sci U S A. 2022. PMID: 35914154 Free PMC article.
Synergistic innate and adaptive immune response to combination immunotherapy with anti-tumor antigen antibodies and extended serum half-life IL-2.
Zhu EF, Gai SA, Opel CF, Kwan BH, Surana R, Mihm MC, Kauke MJ, Moynihan KD, Angelini A, Williams RT, Stephan MT, Kim JS, Yaffe MB, Irvine DJ, Weiner LM, Dranoff G, Wittrup KD. Zhu EF, et al. Among authors: irvine dj. Cancer Cell. 2015 Apr 13;27(4):489-501. doi: 10.1016/j.ccell.2015.03.004. Cancer Cell. 2015. PMID: 25873172 Free PMC article.
Engineering New Approaches to Cancer Vaccines.
Mehta NK, Moynihan KD, Irvine DJ. Mehta NK, et al. Among authors: irvine dj. Cancer Immunol Res. 2015 Aug;3(8):836-43. doi: 10.1158/2326-6066.CIR-15-0112. Epub 2015 Jul 8. Cancer Immunol Res. 2015. PMID: 26156157 Free PMC article. Review.
Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination.
Tam HH, Melo MB, Kang M, Pelet JM, Ruda VM, Foley MH, Hu JK, Kumari S, Crampton J, Baldeon AD, Sanders RW, Moore JP, Crotty S, Langer R, Anderson DG, Chakraborty AK, Irvine DJ. Tam HH, et al. Among authors: irvine dj. Proc Natl Acad Sci U S A. 2016 Oct 25;113(43):E6639-E6648. doi: 10.1073/pnas.1606050113. Epub 2016 Oct 4. Proc Natl Acad Sci U S A. 2016. PMID: 27702895 Free PMC article.
329 results