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Cell-type-specific cis-eQTLs in eight human brain cell types identify novel risk genes for psychiatric and neurological disorders.
Bryois J, Calini D, Macnair W, Foo L, Urich E, Ortmann W, Iglesias VA, Selvaraj S, Nutma E, Marzin M, Amor S, Williams A, Castelo-Branco G, Menon V, De Jager P, Malhotra D. Bryois J, et al. Among authors: menon v. Nat Neurosci. 2022 Aug;25(8):1104-1112. doi: 10.1038/s41593-022-01128-z. Epub 2022 Aug 1. Nat Neurosci. 2022. PMID: 35915177
Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.
Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostafavi S; CommonMind Consortium (CMC); The AMP-AD Consortium; Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM. Sieberts SK, et al. Sci Data. 2020 Oct 12;7(1):340. doi: 10.1038/s41597-020-00642-8. Sci Data. 2020. PMID: 33046718 Free PMC article.
Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease.
Olah M, Menon V, Habib N, Taga MF, Ma Y, Yung CJ, Cimpean M, Khairallah A, Coronas-Samano G, Sankowski R, Grün D, Kroshilina AA, Dionne D, Sarkis RA, Cosgrove GR, Helgager J, Golden JA, Pennell PB, Prinz M, Vonsattel JPG, Teich AF, Schneider JA, Bennett DA, Regev A, Elyaman W, Bradshaw EM, De Jager PL. Olah M, et al. Among authors: menon v. Nat Commun. 2020 Nov 30;11(1):6129. doi: 10.1038/s41467-020-19737-2. Nat Commun. 2020. PMID: 33257666 Free PMC article.
Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors.
Lagomarsino VN, Pearse RV 2nd, Liu L, Hsieh YC, Fernandez MA, Vinton EA, Paull D, Felsky D, Tasaki S, Gaiteri C, Vardarajan B, Lee H, Muratore CR, Benoit CR, Chou V, Fancher SB, He A, Merchant JP, Duong DM, Martinez H, Zhou M, Bah F, Vicent MA, Stricker JMS, Xu J, Dammer EB, Levey AI, Chibnik LB, Menon V, Seyfried NT, De Jager PL, Noggle S, Selkoe DJ, Bennett DA, Young-Pearse TL. Lagomarsino VN, et al. Among authors: menon v. Neuron. 2021 Nov 3;109(21):3402-3420.e9. doi: 10.1016/j.neuron.2021.08.003. Epub 2021 Sep 1. Neuron. 2021. PMID: 34473944 Free PMC article.
RNASE6 is a novel modifier of APOE-ε4 effects on cognition.
Seto M, Weiner RL, Dumitrescu L, Mahoney ER, Hansen SL, Janve V, Khan OA, Liu D, Wang Y, Menon V, De Jager PL, Schneider JA, Bennett DA, Gifford KA, Jefferson AL, Hohman TJ. Seto M, et al. Among authors: menon v. Neurobiol Aging. 2022 Oct;118:66-76. doi: 10.1016/j.neurobiolaging.2022.06.011. Epub 2022 Jul 1. Neurobiol Aging. 2022. PMID: 35896049 Free PMC article.
Multi-omic characterization of brain changes in the vascular endothelial growth factor family during aging and Alzheimer's disease.
Seto M, Dumitrescu L, Mahoney ER, Sclafani AM, De Jager PL, Menon V, Koran MEI, Robinson RA, Ruderfer DM, Cox NJ, Seyfried NT, Jefferson AL, Schneider JA, Bennett DA, Petyuk VA, Hohman TJ. Seto M, et al. Among authors: menon v. Neurobiol Aging. 2023 Jun;126:25-33. doi: 10.1016/j.neurobiolaging.2023.01.010. Epub 2023 Jan 26. Neurobiol Aging. 2023. PMID: 36905877 Free PMC article.
1,998 results