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208 results

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Page 1
A cross-disorder dosage sensitivity map of the human genome.
Collins RL, Glessner JT, Porcu E, Lepamets M, Brandon R, Lauricella C, Han L, Morley T, Niestroj LM, Ulirsch J, Everett S, Howrigan DP, Boone PM, Fu J, Karczewski KJ, Kellaris G, Lowther C, Lucente D, Mohajeri K, Nõukas M, Nuttle X, Samocha KE, Trinh M, Ullah F, Võsa U; Epi25 Consortium; Estonian Biobank Research Team; Hurles ME, Aradhya S, Davis EE, Finucane H, Gusella JF, Janze A, Katsanis N, Matyakhina L, Neale BM, Sanders D, Warren S, Hodge JC, Lal D, Ruderfer DM, Meck J, Mägi R, Esko T, Reymond A, Kutalik Z, Hakonarson H, Sunyaev S, Brand H, Talkowski ME. Collins RL, et al. Among authors: morley t. Cell. 2022 Aug 4;185(16):3041-3055.e25. doi: 10.1016/j.cell.2022.06.036. Epub 2022 Aug 1. Cell. 2022. PMID: 35917817 Free PMC article.
Convergent coexpression of autism-associated genes suggests some novel risk genes may not be detectable in large-scale genetic studies.
Liao C, Moyses-Oliveira M, De Esch CEF, Bhavsar R, Nuttle X, Li A, Yu A, Burt ND, Erdin S, Fu JM, Wang M, Morley T, Han L; CommonMind Consortium; Dion PA, Rouleau GA, Zhang B, Brennand KJ, Talkowski ME, Ruderfer DM. Liao C, et al. Among authors: morley t. Cell Genom. 2023 Mar 9;3(4):100277. doi: 10.1016/j.xgen.2023.100277. eCollection 2023 Apr 12. Cell Genom. 2023. PMID: 37082147 Free PMC article.
Identifying modifiable comorbidities of schizophrenia by integrating electronic health records and polygenic risk.
Vessels T, Strayer N, Choi KW, Lee H, Zhang S, Han L, Morley TJ, Smoller JW, Xu Y, Ruderfer DM. Vessels T, et al. Among authors: morley tj. medRxiv [Preprint]. 2023 Jun 5:2023.06.01.23290057. doi: 10.1101/2023.06.01.23290057. medRxiv. 2023. Update in: Biol Psychiatry Glob Open Sci. 2024 Feb 28;4(3):100297. doi: 10.1016/j.bpsgos.2024.100297 PMID: 37333378 Free PMC article. Updated. Preprint.
Evaluating the impact of modeling choices on the performance of integrated genetic and clinical models.
Morley TJ, Willimitis D, Ripperger M, Lee H, Han L, Zhou Y, Kang J, Davis LK, Smoller JW, Choi KW, Walsh CG, Ruderfer DM. Morley TJ, et al. medRxiv [Preprint]. 2023 Nov 1:2023.11.01.23297927. doi: 10.1101/2023.11.01.23297927. medRxiv. 2023. Update in: Genet Med. 2024 Dec 26:101353. doi: 10.1016/j.gim.2024.101353 PMID: 37961557 Free PMC article. Updated. Preprint.
Integrating Electronic Health Records and Polygenic Risk to Identify Genetically Unrelated Comorbidities of Schizophrenia That May Be Modifiable.
Vessels T, Strayer N, Lee H, Choi KW, Zhang S, Han L, Morley TJ, Smoller JW, Xu Y, Ruderfer DM. Vessels T, et al. Among authors: morley tj. Biol Psychiatry Glob Open Sci. 2024 Feb 28;4(3):100297. doi: 10.1016/j.bpsgos.2024.100297. eCollection 2024 May. Biol Psychiatry Glob Open Sci. 2024. PMID: 38645405 Free PMC article.
Genome-Wide Association Study of Treatment-Resistant Depression: Shared Biology With Metabolic Traits.
Kang J, Castro VM, Ripperger M, Venkatesh S, Burstein D, Linnér RK, Rocha DB, Hu Y, Wilimitis D, Morley T, Han L, Kim RY, Feng YA, Ge T, Heckers S, Voloudakis G, Chabris C, Roussos P, McCoy TH, Walsh CG, Perlis RH, Ruderfer DM. Kang J, et al. Among authors: morley t. Am J Psychiatry. 2024 Jul 1;181(7):608-619. doi: 10.1176/appi.ajp.20230247. Epub 2024 May 15. Am J Psychiatry. 2024. PMID: 38745458
208 results