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Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs.
Johannes JW, Balazs A, Barratt D, Bista M, Chuba MD, Cosulich S, Critchlow SE, Degorce SL, Di Fruscia P, Edmondson SD, Embrey K, Fawell S, Ghosh A, Gill SJ, Gunnarsson A, Hande SM, Heightman TD, Hemsley P, Illuzzi G, Lane J, Larner C, Leo E, Liu L, Madin A, Martin S, McWilliams L, O'Connor MJ, Orme JP, Pachl F, Packer MJ, Pei X, Pike A, Schimpl M, She H, Staniszewska AD, Talbot V, Underwood E, Varnes JG, Xue L, Yao T, Zhang K, Zhang AX, Zheng X. Johannes JW, et al. Among authors: lane j. J Med Chem. 2021 Oct 14;64(19):14498-14512. doi: 10.1021/acs.jmedchem.1c01012. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34570508
A PCR-based linkage map of human chromosome 1.
Engelstein M, Hudson TJ, Lane JM, Lee MK, Leverone B, Landes GM, Peltonen L, Weber JL, Dracopoli NC. Engelstein M, et al. Among authors: lane jm. Genomics. 1993 Feb;15(2):251-8. doi: 10.1006/geno.1993.1054. Genomics. 1993. PMID: 8449488
Addressing evidence needs during health crises in the province of Quebec (Canada): a proposed action plan for rapid evidence synthesis.
Hong QN, McSween-Cadieux E, Guillette M, Manceau LM, Li J, Granikov V, Pomey MP, Gagnon MP, Ziam S, Dagenais C, Dagenais P, Lesage A, Poder TG, Drapeau M, Ridde V, Lane J. Hong QN, et al. Among authors: lane j. BMC Health Serv Res. 2025 Jan 11;25(1):61. doi: 10.1186/s12913-025-12204-y. BMC Health Serv Res. 2025. PMID: 39799371
3,260 results