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Inhibition of polyploidization in Pten-deficient livers reduces steatosis.
Moreno E, Matondo AB, Bongiovanni L, van de Lest CHA, Molenaar MR, Toussaint MJM, van Essen SC, Houweling M, Helms JB, Westendorp B, de Bruin A. Moreno E, et al. Among authors: toussaint mjm. Liver Int. 2022 Nov;42(11):2442-2452. doi: 10.1111/liv.15384. Epub 2022 Sep 2. Liver Int. 2022. PMID: 35924448 Free PMC article.
E2F8 is essential for polyploidization in mammalian cells.
Pandit SK, Westendorp B, Nantasanti S, van Liere E, Tooten PC, Cornelissen PW, Toussaint MJ, Lamers WH, de Bruin A. Pandit SK, et al. Nat Cell Biol. 2012 Nov;14(11):1181-91. doi: 10.1038/ncb2585. Epub 2012 Oct 14. Nat Cell Biol. 2012. PMID: 23064264
Atypical E2f functions are critical for pancreas polyploidization.
Matondo RB, Moreno E, Toussaint MJM, Tooten PCJ, van Essen SC, van Liere EA, Youssef SA, Bongiovanni L, de Bruin A. Matondo RB, et al. Among authors: toussaint mjm. PLoS One. 2018 Jan 12;13(1):e0190899. doi: 10.1371/journal.pone.0190899. eCollection 2018. PLoS One. 2018. PMID: 29329320 Free PMC article.
E2F7 Is a Potent Inhibitor of Liver Tumor Growth in Adult Mice.
Moreno E, Toussaint MJM, van Essen SC, Bongiovanni L, van Liere EA, Koster MH, Yuan R, van Deursen JM, Westendorp B, de Bruin A. Moreno E, et al. Among authors: toussaint mjm. Hepatology. 2021 Jan;73(1):303-317. doi: 10.1002/hep.31259. Hepatology. 2021. PMID: 32259305 Free PMC article.
DYRK1A Is a Regulator of S-Phase Entry in Hepatic Progenitor Cells.
Kruitwagen HS, Westendorp B, Viebahn CS, Post K, van Wolferen ME, Oosterhoff LA, Egan DA, Delabar JM, Toussaint MJ, Schotanus BA, de Bruin A, Rothuizen J, Penning LC, Spee B. Kruitwagen HS, et al. Stem Cells Dev. 2018 Jan 15;27(2):133-146. doi: 10.1089/scd.2017.0139. Epub 2018 Jan 3. Stem Cells Dev. 2018. PMID: 29179659
Surgical resection and radiofrequency ablation initiate cancer in cytokeratin-19+- liver cells deficient for p53 and Rb.
Matondo RB, Toussaint MJ, Govaert KM, van Vuuren LD, Nantasanti S, Nijkamp MW, Pandit SK, Tooten PC, Koster MH, Holleman K, Schot A, Gu G, Spee B, Roskams T, Rinkes IB, Schotanus B, Kranenburg O, de Bruin A. Matondo RB, et al. Oncotarget. 2016 Aug 23;7(34):54662-54675. doi: 10.18632/oncotarget.9952. Oncotarget. 2016. PMID: 27323406 Free PMC article.
37 results