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Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors.
Huff S, Kummetha IR, Tiwari SK, Huante MB, Clark AE, Wang S, Bray W, Smith D, Carlin AF, Endsley M, Rana TM. Huff S, et al. Among authors: bray w. J Med Chem. 2022 Feb 24;65(4):2866-2879. doi: 10.1021/acs.jmedchem.1c00566. Epub 2021 Sep 27. J Med Chem. 2022. PMID: 34570513 Free PMC article.
1-O-Octadecyl-2-O-benzyl-sn-glyceryl-3-phospho-GS-441524 (V2043). Evaluation of Oral V2043 in a Mouse Model of SARS-CoV-2 Infection and Synthesis and Antiviral Evaluation of Additional Phospholipid Esters with Enhanced Anti-SARS-CoV-2 Activity.
Carlin AF, Beadle JR, Clark AE, Gully KL, Moreira FR, Baric RS, Graham RL, Valiaeva N, Leibel SL, Bray W, McMillan RE, Freshman JE, Garretson AF, McVicar RN, Rana T, Zhang XQ, Murphy JA, Schooley RT, Hostetler KY. Carlin AF, et al. Among authors: bray w. J Med Chem. 2023 Apr 27;66(8):5802-5819. doi: 10.1021/acs.jmedchem.3c00046. Epub 2023 Apr 11. J Med Chem. 2023. PMID: 37040439 Free PMC article.
Neutralizing Antibody Responses After Severe Acute Respiratory Syndrome Coronavirus 2 BA.2 and BA.2.12.1 Infection Do Not Neutralize BA.4 and BA.5 and Can Be Blunted by Nirmatrelvir/Ritonavir Treatment.
Carlin AF, Clark AE, Garretson AF, Bray W, Porrachia M, Santos AT, Rana TM, Chaillon A, Smith DM. Carlin AF, et al. Among authors: bray w. Open Forum Infect Dis. 2023 Mar 21;10(4):ofad154. doi: 10.1093/ofid/ofad154. eCollection 2023 Apr. Open Forum Infect Dis. 2023. PMID: 37096144 Free PMC article.
Interferon-Inducible Guanylate-Binding Protein 5 Inhibits Replication of Multiple Viruses by Binding to the Oligosaccharyltransferase Complex and Inhibiting Glycoprotein Maturation.
Wang S, Li W, Wang L, Tiwari SK, Bray W, Wu L, Li N, Hui H, Clark AE, Zhang Q, Zhang L, Carlin AF, Rana TM. Wang S, et al. Among authors: bray w. bioRxiv [Preprint]. 2024 May 3:2024.05.01.591800. doi: 10.1101/2024.05.01.591800. bioRxiv. 2024. PMID: 38746287 Free PMC article. Preprint.
Antibody Levels from High-Throughput Variant-Specific SARS-CoV-2 Anti-Spike IgG and ACE2 Neutralization Assays Correlate with COVID Infection Risk in a Large Population.
Jacobs MB, Clark AE, Goldhaber NH, Valentine HD, Rivera A, Ngo T, Barber T, Holmes J, Manfredi B, Garretson AF, Bray W, Knight R, Longhurst CA, Carlin AF, De Hoff P, Laurent LC. Jacobs MB, et al. Among authors: bray w. J Infect Dis. 2024 Dec 16:jiae622. doi: 10.1093/infdis/jiae622. Online ahead of print. J Infect Dis. 2024. PMID: 39676529
Virologic and Immunologic Characterization of COVID-19 Recrudescence after Nirmatrelvir/Ritonavir Treatment.
Carlin AF, Clark AE, Chaillon A, Garretson AF, Bray W, Porrachi M, Santos AT, Smith DM. Carlin AF, et al. Among authors: bray w. Res Sq [Preprint]. 2022 May 18:rs.3.rs-1662783. doi: 10.21203/rs.3.rs-1662783/v1. Res Sq. 2022. Update in: Clin Infect Dis. 2023 Feb 8;76(3):e530-e532. doi: 10.1093/cid/ciac496 PMID: 35611335 Free PMC article. Updated. Preprint.
78 results