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The relationship between the epigenetic aging biomarker "grimage" and lung function in both the airway and blood of people living with HIV: An observational cohort study.
Hernández Cordero AI, Yang CX, Yang J, Li X, Horvath S, Shaipanich T, MacIsaac J, Lin D, McEwen L, Kobor MS, Guillemi S, Harris M, Lam W, Lam S, Obeidat M, Novak RM, Hudson F, Klinker H, Dharan N, Montaner J, Man SFP, Kunisaki K, Sin DD, Leung JM; INSIGHT START Pulmonary and Genomic Substudy Groups. Hernández Cordero AI, et al. Among authors: li x. EBioMedicine. 2022 Sep;83:104206. doi: 10.1016/j.ebiom.2022.104206. Epub 2022 Aug 6. EBioMedicine. 2022. PMID: 35944348 Free PMC article.
Integrative Genomics of Emphysema-Associated Genes Reveals Potential Disease Biomarkers.
Obeidat M, Nie Y, Fishbane N, Li X, Bossé Y, Joubert P, Nickle DC, Hao K, Postma DS, Timens W, Sze MA, Shannon CP, Hollander Z, Ng RT, McManus B, Miller BE, Rennard S, Spira A, Hackett TL, Lam W, Lam S, Faner R, Agusti A, Hogg JC, Sin DD, Paré PD. Obeidat M, et al. Among authors: li x. Am J Respir Cell Mol Biol. 2017 Oct;57(4):411-418. doi: 10.1165/rcmb.2016-0284OC. Am J Respir Cell Mol Biol. 2017. PMID: 28459279 Free PMC article.
Surfactant protein D is a causal risk factor for COPD: results of Mendelian randomisation.
Obeidat M, Li X, Burgess S, Zhou G, Fishbane N, Hansel NN, Bossé Y, Joubert P, Hao K, Nickle DC, van den Berge M, Timens W, Cho MH, Hobbs BD, de Jong K, Boezen M, Hung RJ, Rafaels N, Mathias R, Ruczinski I, Beaty TH, Barnes KC, Paré PD, Sin DD; International COPD Genetics Consortium, Lung eQTL Consortium, Lung Health Study. Obeidat M, et al. Among authors: li x. Eur Respir J. 2017 Nov 30;50(5):1700657. doi: 10.1183/13993003.00657-2017. Print 2017 Nov. Eur Respir J. 2017. PMID: 29191953 Free PMC article.
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries.
Shrine N, Guyatt AL, Erzurumluoglu AM, Jackson VE, Hobbs BD, Melbourne CA, Batini C, Fawcett KA, Song K, Sakornsakolpat P, Li X, Boxall R, Reeve NF, Obeidat M, Zhao JH, Wielscher M, Weiss S, Kentistou KA, Cook JP, Sun BB, Zhou J, Hui J, Karrasch S, Imboden M, Harris SE, Marten J, Enroth S, Kerr SM, Surakka I, Vitart V, Lehtimäki T, Allen RJ, Bakke PS, Beaty TH, Bleecker ER, Bossé Y, Brandsma CA, Chen Z, Crapo JD, Danesh J, DeMeo DL, Dudbridge F, Ewert R, Gieger C, Gulsvik A, Hansell AL, Hao K, Hoffman JD, Hokanson JE, Homuth G, Joshi PK, Joubert P, Langenberg C, Li X, Li L, Lin K, Lind L, Locantore N, Luan J, Mahajan A, Maranville JC, Murray A, Nickle DC, Packer R, Parker MM, Paynton ML, Porteous DJ, Prokopenko D, Qiao D, Rawal R, Runz H, Sayers I, Sin DD, Smith BH, Soler Artigas M, Sparrow D, Tal-Singer R, Timmers PRHJ, Van den Berge M, Whittaker JC, Woodruff PG, Yerges-Armstrong LM, Troyanskaya OG, Raitakari OT, Kähönen M, Polašek O, Gyllensten U, Rudan I, Deary IJ, Probst-Hensch NM, Schulz H, James AL, Wilson JF, Stubbe B, Zeggini E, Jarvelin MR, Wareham N, Silverman EK, Hayward C, Morris AP, Butterworth AS, Scott RA, Walters RG, Meyers DA, Cho MH, Strachan… See abstract for full author list ➔ Shrine N, et al. Among authors: li x, li l. Nat Genet. 2019 Mar;51(3):481-493. doi: 10.1038/s41588-018-0321-7. Epub 2019 Feb 25. Nat Genet. 2019. PMID: 30804560 Free PMC article.
The pharmacogenomics of inhaled corticosteroids and lung function decline in COPD.
Obeidat M, Faiz A, Li X, van den Berge M, Hansel NN, Joubert P, Hao K, Brandsma CA, Rafaels N, Mathias R, Ruczinski I, Beaty TH, Barnes KC, Man SFP, Paré PD, Sin DD. Obeidat M, et al. Among authors: li x. Eur Respir J. 2019 Dec 4;54(6):1900521. doi: 10.1183/13993003.00521-2019. Print 2019 Dec. Eur Respir J. 2019. PMID: 31537701 Free article. Clinical Trial.
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