Mesrouze Y - Search Results

1

The First Class of Small Molecules Potently Disrupting the YAP-TEAD Interaction by Direct Competition.

Furet P, Bordas V, Le Douget M, Salem B, Mesrouze Y, Imbach-Weese P, Sellner H, Voegtle M, Soldermann N, Chapeau E, Wartmann M, Scheufler C, Fernandez C, Kallen J, Guagnano V, Chène P, Schmelzle T. Furet P, et al. Among authors: mesrouze y. ChemMedChem. 2022 Oct 6;17(19):e202200303. doi: 10.1002/cmdc.202200303. Epub 2022 Sep 2. ChemMedChem. 2022. PMID: 35950546

2

The TEAD4-YAP/TAZ protein-protein interaction: expected similarities and unexpected differences.

Hau JC, Erdmann D, Mesrouze Y, Furet P, Fontana P, Zimmermann C, Schmelzle T, Hofmann F, Chène P. Hau JC, et al. Among authors: mesrouze y. Chembiochem. 2013 Jul 8;14(10):1218-25. doi: 10.1002/cbic.201300163. Epub 2013 Jun 18. Chembiochem. 2013. PMID: 23780915

3

The surprising features of the TEAD4-Vgll1 protein-protein interaction.

Mesrouze Y, Hau JC, Erdmann D, Zimmermann C, Fontana P, Schmelzle T, Chène P. Mesrouze Y, et al. Chembiochem. 2014 Mar 3;15(4):537-42. doi: 10.1002/cbic.201300715. Epub 2014 Feb 6. Chembiochem. 2014. PMID: 24504694

4

Dissection of the interaction between the intrinsically disordered YAP protein and the transcription factor TEAD.

Mesrouze Y, Bokhovchuk F, Meyerhofer M, Fontana P, Zimmermann C, Martin T, Delaunay C, Erdmann D, Schmelzle T, Chène P. Mesrouze Y, et al. Elife. 2017 Apr 21;6:e25068. doi: 10.7554/eLife.25068. Elife. 2017. PMID: 28430104 Free PMC article.

5

Effect of the acylation of TEAD4 on its interaction with co-activators YAP and TAZ.

Mesrouze Y, Meyerhofer M, Bokhovchuk F, Fontana P, Zimmermann C, Martin T, Delaunay C, Izaac A, Kallen J, Schmelzle T, Erdmann D, Chène P. Mesrouze Y, et al. Protein Sci. 2017 Dec;26(12):2399-2409. doi: 10.1002/pro.3312. Epub 2017 Nov 11. Protein Sci. 2017. PMID: 28960584 Free PMC article.

6

Adaptation of the bound intrinsically disordered protein YAP to mutations at the YAP:TEAD interface.

Mesrouze Y, Bokhovchuk F, Izaac A, Meyerhofer M, Zimmermann C, Fontana P, Schmelzle T, Erdmann D, Furet P, Kallen J, Chène P. Mesrouze Y, et al. Protein Sci. 2018 Oct;27(10):1810-1820. doi: 10.1002/pro.3493. Protein Sci. 2018. PMID: 30058229 Free PMC article.

7

Molecular and structural characterization of a TEAD mutation at the origin of Sveinsson's chorioretinal atrophy.

Bokhovchuk F, Mesrouze Y, Izaac A, Meyerhofer M, Zimmermann C, Fontana P, Schmelzle T, Erdmann D, Furet P, Kallen J, Chène P. Bokhovchuk F, et al. Among authors: mesrouze y. FEBS J. 2019 Jun;286(12):2381-2398. doi: 10.1111/febs.14817. Epub 2019 Apr 11. FEBS J. 2019. PMID: 30903741 Free article.

8

Structure-based design of potent linear peptide inhibitors of the YAP-TEAD protein-protein interaction derived from the YAP omega-loop sequence.

Furet P, Salem B, Mesrouze Y, Schmelzle T, Lewis I, Kallen J, Chène P. Furet P, et al. Among authors: mesrouze y. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2316-2319. doi: 10.1016/j.bmcl.2019.06.022. Epub 2019 Jun 18. Bioorg Med Chem Lett. 2019. PMID: 31235263

9

Identification of FAM181A and FAM181B as new interactors with the TEAD transcription factors.

Bokhovchuk F, Mesrouze Y, Delaunay C, Martin T, Villard F, Meyerhofer M, Fontana P, Zimmermann C, Erdmann D, Furet P, Scheufler C, Schmelzle T, Chène P. Bokhovchuk F, et al. Among authors: mesrouze y. Protein Sci. 2020 Feb;29(2):509-520. doi: 10.1002/pro.3775. Epub 2019 Nov 20. Protein Sci. 2020. PMID: 31697419 Free PMC article.

10

An Early Association between the α-Helix of the TEAD Binding Domain of YAP and TEAD Drives the Formation of the YAP:TEAD Complex.

Bokhovchuk F, Mesrouze Y, Meyerhofer M, Zimmermann C, Fontana P, Erdmann D, Jemth P, Chène P. Bokhovchuk F, et al. Among authors: mesrouze y. Biochemistry. 2020 May 19;59(19):1804-1812. doi: 10.1021/acs.biochem.0c00217. Epub 2020 Apr 30. Biochemistry. 2020. PMID: 32329346

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