Alessi DR - Search Results

1

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding.

Kalogeropulou AF, Purlyte E, Tonelli F, Lange SM, Wightman M, Prescott AR, Padmanabhan S, Sammler E, Alessi DR. Kalogeropulou AF, et al. Among authors: alessi dr. Biochem J. 2022 Sep 16;479(17):1759-1783. doi: 10.1042/BCJ20220161. Biochem J. 2022. PMID: 35950872 Free PMC article.

2

Specific binding of the Akt-1 protein kinase to phosphatidylinositol 3,4,5-trisphosphate without subsequent activation.

James SR, Downes CP, Gigg R, Grove SJ, Holmes AB, Alessi DR. James SR, et al. Among authors: alessi dr. Biochem J. 1996 May 1;315 ( Pt 3)(Pt 3):709-13. doi: 10.1042/bj3150709. Biochem J. 1996. PMID: 8645147 Free PMC article.

3

Activation of protein kinase B beta and gamma isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: comparison with protein kinase B alpha.

Walker KS, Deak M, Paterson A, Hudson K, Cohen P, Alessi DR. Walker KS, et al. Among authors: alessi dr. Biochem J. 1998 Apr 1;331 ( Pt 1)(Pt 1):299-308. doi: 10.1042/bj3310299. Biochem J. 1998. PMID: 9512493 Free PMC article.

4

The activation of protein kinase B by H2O2 or heat shock is mediated by phosphoinositide 3-kinase and not by mitogen-activated protein kinase-activated protein kinase-2.

Shaw M, Cohen P, Alessi DR. Shaw M, et al. Among authors: alessi dr. Biochem J. 1998 Nov 15;336 ( Pt 1)(Pt 1):241-6. doi: 10.1042/bj3360241. Biochem J. 1998. PMID: 9806907 Free PMC article.

5

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1.

Currie RA, Walker KS, Gray A, Deak M, Casamayor A, Downes CP, Cohen P, Alessi DR, Lucocq J. Currie RA, et al. Among authors: alessi dr. Biochem J. 1999 Feb 1;337 ( Pt 3)(Pt 3):575-83. Biochem J. 1999. PMID: 9895304 Free PMC article.

6

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo.

Casamayor A, Morrice NA, Alessi DR. Casamayor A, et al. Among authors: alessi dr. Biochem J. 1999 Sep 1;342 ( Pt 2)(Pt 2):287-92. Biochem J. 1999. PMID: 10455013 Free PMC article.

7

Phosphoinositide 3-kinase-dependent phosphorylation of the dual adaptor for phosphotyrosine and 3-phosphoinositides by the Src family of tyrosine kinase.

Dowler S, Montalvo L, Cantrell D, Morrice N, Alessi DR. Dowler S, et al. Among authors: alessi dr. Biochem J. 2000 Jul 15;349(Pt 2):605-10. doi: 10.1042/0264-6021:3490605. Biochem J. 2000. PMID: 10880360 Free PMC article.

8

Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities.

Dowler S, Currie RA, Campbell DG, Deak M, Kular G, Downes CP, Alessi DR. Dowler S, et al. Among authors: alessi dr. Biochem J. 2000 Oct 1;351(Pt 1):19-31. doi: 10.1042/0264-6021:3510019. Biochem J. 2000. PMID: 11001876 Free PMC article.

9

Discovery of PDK1, one of the missing links in insulin signal transduction. Colworth Medal Lecture.

Alessi DR. Alessi DR. Biochem Soc Trans. 2001 May;29(Pt 2):1-14. doi: 10.1042/0300-5127:0290001. Biochem Soc Trans. 2001. PMID: 11356119

10

Identification and characterization of four novel phosphorylation sites (Ser31, Ser325, Thr336 and Thr366) on LKB1/STK11, the protein kinase mutated in Peutz-Jeghers cancer syndrome.

Sapkota GP, Boudeau J, Deak M, Kieloch A, Morrice N, Alessi DR. Sapkota GP, et al. Among authors: alessi dr. Biochem J. 2002 Mar 1;362(Pt 2):481-90. doi: 10.1042/0264-6021:3620481. Biochem J. 2002. PMID: 11853558 Free PMC article.

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