Prescott AR - Search Results

1

Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding.

Kalogeropulou AF, Purlyte E, Tonelli F, Lange SM, Wightman M, Prescott AR, Padmanabhan S, Sammler E, Alessi DR. Kalogeropulou AF, et al. Among authors: prescott ar. Biochem J. 2022 Sep 16;479(17):1759-1783. doi: 10.1042/BCJ20220161. Biochem J. 2022. PMID: 35950872 Free PMC article.

2

A role for the actin cytoskeleton in the hormonal and growth-factor-mediated activation of protein kinase B.

Peyrollier K, Hajduch E, Gray A, Litherland GJ, Prescott AR, Leslie NR, Hundal HS. Peyrollier K, et al. Among authors: prescott ar. Biochem J. 2000 Dec 15;352 Pt 3(Pt 3):617-22. Biochem J. 2000. PMID: 11104665 Free PMC article.

3

Roles of the forkhead in rhabdomyosarcoma (FKHR) phosphorylation sites in regulating 14-3-3 binding, transactivation and nuclear targetting.

Rena G, Prescott AR, Guo S, Cohen P, Unterman TG. Rena G, et al. Among authors: prescott ar. Biochem J. 2001 Mar 15;354(Pt 3):605-12. doi: 10.1042/0264-6021:3540605. Biochem J. 2001. PMID: 11237865 Free PMC article.

4

Essential role of PDK1 in regulating cell size and development in mice.

Lawlor MA, Mora A, Ashby PR, Williams MR, Murray-Tait V, Malone L, Prescott AR, Lucocq JM, Alessi DR. Lawlor MA, et al. Among authors: prescott ar. EMBO J. 2002 Jul 15;21(14):3728-38. doi: 10.1093/emboj/cdf387. EMBO J. 2002. PMID: 12110585 Free PMC article.

5

Interaction of the protein tyrosine phosphatase PTPL1 with the PtdIns(3,4)P2-binding adaptor protein TAPP1.

Kimber WA, Deak M, Prescott AR, Alessi DR. Kimber WA, et al. Among authors: prescott ar. Biochem J. 2003 Dec 1;376(Pt 2):525-35. doi: 10.1042/BJ20031154. Biochem J. 2003. PMID: 14516276 Free PMC article.

6

MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm.

Boudeau J, Baas AF, Deak M, Morrice NA, Kieloch A, Schutkowski M, Prescott AR, Clevers HC, Alessi DR. Boudeau J, et al. Among authors: prescott ar. EMBO J. 2003 Oct 1;22(19):5102-14. doi: 10.1093/emboj/cdg490. EMBO J. 2003. PMID: 14517248 Free PMC article.

7

WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate.

Vitari AC, Deak M, Collins BJ, Morrice N, Prescott AR, Phelan A, Humphreys S, Alessi DR. Vitari AC, et al. Among authors: prescott ar. Biochem J. 2004 Feb 15;378(Pt 1):257-68. doi: 10.1042/BJ20031692. Biochem J. 2004. PMID: 14611643 Free PMC article.

8

The in vivo role of PtdIns(3,4,5)P3 binding to PDK1 PH domain defined by knockin mutation.

McManus EJ, Collins BJ, Ashby PR, Prescott AR, Murray-Tait V, Armit LJ, Arthur JS, Alessi DR. McManus EJ, et al. Among authors: prescott ar. EMBO J. 2004 May 19;23(10):2071-82. doi: 10.1038/sj.emboj.7600218. Epub 2004 Apr 29. EMBO J. 2004. PMID: 15116068 Free PMC article.

9

Structural insights into the regulation of PDK1 by phosphoinositides and inositol phosphates.

Komander D, Fairservice A, Deak M, Kular GS, Prescott AR, Peter Downes C, Safrany ST, Alessi DR, van Aalten DM. Komander D, et al. Among authors: prescott ar. EMBO J. 2004 Oct 13;23(20):3918-28. doi: 10.1038/sj.emboj.7600379. Epub 2004 Sep 30. EMBO J. 2004. PMID: 15457207 Free PMC article.

10

Analysis of the LKB1-STRAD-MO25 complex.

Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR. Boudeau J, et al. Among authors: prescott ar. J Cell Sci. 2004 Dec 15;117(Pt 26):6365-75. doi: 10.1242/jcs.01571. Epub 2004 Nov 23. J Cell Sci. 2004. PMID: 15561763

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