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Activation of non-classical NMDA receptors by glycine impairs barrier function of brain endothelial cells.
Epping L, Schroeter CB, Nelke C, Bock S, Gola L, Ritter N, Herrmann AM, Räuber S, Henes A, Wasser B, Fernandez-Orth J, Neuhaus W, Bittner S, Budde T, Platten M, Kovac S, Seebohm G, Ruck T, Cerina M, Meuth SG. Epping L, et al. Among authors: platten m. Cell Mol Life Sci. 2022 Aug 11;79(9):479. doi: 10.1007/s00018-022-04502-z. Cell Mol Life Sci. 2022. PMID: 35951110 Free PMC article.
Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis.
Lanz TV, Becker S, Osswald M, Bittner S, Schuhmann MK, Opitz CA, Gaikwad S, Wiestler B, Litzenburger UM, Sahm F, Ott M, Iwantscheff S, Grabitz C, Mittelbronn M, von Deimling A, Winkler F, Meuth SG, Wick W, Platten M. Lanz TV, et al. Among authors: platten m. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14735-40. doi: 10.1073/pnas.1302569110. Epub 2013 Aug 19. Proc Natl Acad Sci U S A. 2013. PMID: 23959874 Free PMC article.
Dietary tryptophan links encephalogenicity of autoreactive T cells with gut microbial ecology.
Sonner JK, Keil M, Falk-Paulsen M, Mishra N, Rehman A, Kramer M, Deumelandt K, Röwe J, Sanghvi K, Wolf L, von Landenberg A, Wolff H, Bharti R, Oezen I, Lanz TV, Wanke F, Tang Y, Brandao I, Mohapatra SR, Epping L, Grill A, Röth R, Niesler B, Meuth SG, Opitz CA, Okun JG, Reinhardt C, Kurschus FC, Wick W, Bode HB, Rosenstiel P, Platten M. Sonner JK, et al. Among authors: platten m. Nat Commun. 2019 Oct 25;10(1):4877. doi: 10.1038/s41467-019-12776-4. Nat Commun. 2019. PMID: 31653831 Free PMC article.
Multiple Sclerosis Therapy Consensus Group (MSTCG): position statement on disease-modifying therapies for multiple sclerosis (white paper).
Wiendl H, Gold R, Berger T, Derfuss T, Linker R, Mäurer M, Aktas O, Baum K, Berghoff M, Bittner S, Chan A, Czaplinski A, Deisenhammer F, Di Pauli F, Du Pasquier R, Enzinger C, Fertl E, Gass A, Gehring K, Gobbi C, Goebels N, Guger M, Haghikia A, Hartung HP, Heidenreich F, Hoffmann O, Kallmann B, Kleinschnitz C, Klotz L, Leussink VI, Leutmezer F, Limmroth V, Lünemann JD, Lutterotti A, Meuth SG, Meyding-Lamadé U, Platten M, Rieckmann P, Schmidt S, Tumani H, Weber F, Weber MS, Zettl UK, Ziemssen T, Zipp F; ‘Multiple Sclerosis Therapy Consensus Group’ (MSTCG). Wiendl H, et al. Among authors: platten m. Ther Adv Neurol Disord. 2021 Aug 18;14:17562864211039648. doi: 10.1177/17562864211039648. eCollection 2021. Ther Adv Neurol Disord. 2021. PMID: 34422112 Free PMC article. Review.
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination.
Kapell H, Fazio L, Dyckow J, Schwarz S, Cruz-Herranz A, Mayer C, Campos J, D'Este E, Möbius W, Cordano C, Pröbstel AK, Gharagozloo M, Zulji A, Narayanan Naik V, Delank A, Cerina M, Müntefering T, Lerma-Martin C, Sonner JK, Sin JH, Disse P, Rychlik N, Sabeur K, Chavali M, Srivastava R, Heidenreich M, Fitzgerald KC, Seebohm G, Stadelmann C, Hemmer B, Platten M, Jentsch TJ, Engelhardt M, Budde T, Nave KA, Calabresi PA, Friese MA, Green AJ, Acuna C, Rowitch DH, Meuth SG, Schirmer L. Kapell H, et al. Among authors: platten m. J Clin Invest. 2023 Apr 3;133(7):e164223. doi: 10.1172/JCI164223. J Clin Invest. 2023. PMID: 36719741 Free PMC article.
Endothelial Indoleamine-2,3-Dioxygenase-1 is not Critically Involved in Regulating Antitumor Immunity in the Central Nervous System.
Abu Hejleh AP, Huck K, Jähne K, Tan CL, Lanz TV, Epping L, Sonner JK, Meuth SG, Henneberg A, Opitz CA, Herold-Mende C, Sahm F, Platten M, Sahm K. Abu Hejleh AP, et al. Among authors: platten m. Int J Tryptophan Res. 2023 Feb 9;16:11786469231153111. doi: 10.1177/11786469231153111. eCollection 2023. Int J Tryptophan Res. 2023. PMID: 36798537 Free PMC article.
Concurrent gliomas in patients with multiple sclerosis.
Sahm K, Kessler T, Eisele P, Ratliff M, Sperk E, König L, Breckwoldt MO, Seliger C, Mildenberger I, Schrimpf D, Herold-Mende C, Zeiner PS, Tabatabai G, Meuth SG, Capper D, Bendszus M, von Deimling A, Wick W, Sahm F, Platten M. Sahm K, et al. Among authors: platten m. Commun Med (Lond). 2023 Dec 18;3(1):186. doi: 10.1038/s43856-023-00381-y. Commun Med (Lond). 2023. PMID: 38110626 Free PMC article.
Tryptophan degradation in autoimmune diseases.
Opitz CA, Wick W, Steinman L, Platten M. Opitz CA, et al. Among authors: platten m. Cell Mol Life Sci. 2007 Oct;64(19-20):2542-63. doi: 10.1007/s00018-007-7140-9. Cell Mol Life Sci. 2007. PMID: 17611712 Free PMC article. Review.
Blood-brain barrier and brain edema.
Platten M, Wick W. Platten M, et al. Handb Clin Neurol. 2012;104:53-62. doi: 10.1016/B978-0-444-52138-5.00005-0. Handb Clin Neurol. 2012. PMID: 22230435 Review. No abstract available.
400 results