Zha S - Search Results

1

Revisiting PARP2 and PARP1 trapping through quantitative live-cell imaging.

Zhang H, Lin X, Zha S. Zhang H, et al. Among authors: zha s. Biochem Soc Trans. 2022 Aug 31;50(4):1169-1177. doi: 10.1042/BST20220366. Biochem Soc Trans. 2022. PMID: 35959996

2

CtIP is essential for early B cell proliferation and development in mice.

Liu X, Wang XS, Lee BJ, Wu-Baer FK, Lin X, Shao Z, Estes VM, Gautier J, Baer R, Zha S. Liu X, et al. Among authors: zha s. J Exp Med. 2019 Jul 1;216(7):1648-1663. doi: 10.1084/jem.20181139. Epub 2019 May 16. J Exp Med. 2019. PMID: 31097467 Free PMC article.

3

Phosphorylation at S2053 in Murine (S2056 in Human) DNA-PKcs Is Dispensable for Lymphocyte Development and Class Switch Recombination.

Jiang W, Estes VM, Wang XS, Shao Z, Lee BJ, Lin X, Crowe JL, Zha S. Jiang W, et al. Among authors: zha s. J Immunol. 2019 Jul 1;203(1):178-187. doi: 10.4049/jimmunol.1801657. Epub 2019 May 17. J Immunol. 2019. PMID: 31101667 Free PMC article.

4

LMO2 as a Biomarker for Hypersensitivity to Genotoxic Therapy.

Scuoppo C, Zha S. Scuoppo C, et al. Among authors: zha s. Cancer Cell. 2019 Sep 16;36(3):211-212. doi: 10.1016/j.ccell.2019.08.011. Cancer Cell. 2019. PMID: 31526755 Free article.

5

Clinical PARP inhibitors do not abrogate PARP1 exchange at DNA damage sites in vivo.

Shao Z, Lee BJ, Rouleau-Turcotte É, Langelier MF, Lin X, Estes VM, Pascal JM, Zha S. Shao Z, et al. Among authors: zha s. Nucleic Acids Res. 2020 Sep 25;48(17):9694-9709. doi: 10.1093/nar/gkaa718. Nucleic Acids Res. 2020. PMID: 32890402 Free PMC article.

6

FATC Domain Deletion Compromises ATM Protein Stability, Blocks Lymphocyte Development, and Promotes Lymphomagenesis.

Milanovic M, Shao Z, Estes VM, Wang XS, Menolfi D, Lin X, Lee BJ, Xu J, Cupo OM, Wang D, Zha S. Milanovic M, et al. Among authors: zha s. J Immunol. 2021 Mar 15;206(6):1228-1239. doi: 10.4049/jimmunol.2000967. Epub 2021 Feb 3. J Immunol. 2021. PMID: 33536256 Free PMC article.

7

XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.

Demin AA, Hirota K, Tsuda M, Adamowicz M, Hailstone R, Brazina J, Gittens W, Kalasova I, Shao Z, Zha S, Sasanuma H, Hanzlikova H, Takeda S, Caldecott KW. Demin AA, et al. Among authors: zha s. Mol Cell. 2021 Jul 15;81(14):3018-3030.e5. doi: 10.1016/j.molcel.2021.05.009. Epub 2021 Jun 7. Mol Cell. 2021. PMID: 34102106 Free PMC article.

8

PARP inhibitors trap PARP2 and alter the mode of recruitment of PARP2 at DNA damage sites.

Lin X, Jiang W, Rudolph J, Lee BJ, Luger K, Zha S. Lin X, et al. Among authors: zha s. Nucleic Acids Res. 2022 Apr 22;50(7):3958-3973. doi: 10.1093/nar/gkac188. Nucleic Acids Res. 2022. PMID: 35349716 Free PMC article.

9

Clinical PARP inhibitors allosterically induce PARP2 retention on DNA.

Langelier MF, Lin X, Zha S, Pascal JM. Langelier MF, et al. Among authors: zha s. Sci Adv. 2023 Mar 24;9(12):eadf7175. doi: 10.1126/sciadv.adf7175. Epub 2023 Mar 24. Sci Adv. 2023. PMID: 36961901 Free PMC article.

10

ATR kinase supports normal proliferation in the early S phase by preventing replication resource exhaustion.

Menolfi D, Lee BJ, Zhang H, Jiang W, Bowen NE, Wang Y, Zhao J, Holmes A, Gershik S, Rabadan R, Kim B, Zha S. Menolfi D, et al. Among authors: zha s. Nat Commun. 2023 Jun 19;14(1):3618. doi: 10.1038/s41467-023-39332-5. Nat Commun. 2023. PMID: 37336885 Free PMC article.

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