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Page 1
Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.
Rosenberg N, Van Haele M, Lanton T, Brashi N, Bromberg Z, Adler H, Giladi H, Peled A, Goldenberg DS, Axelrod JH, Simerzin A, Chai C, Paldor M, Markezana A, Yaish D, Shemulian Z, Gross D, Barnoy S, Gefen M, Amran O, Claerhout S, Fernández-Vaquero M, García-Beccaria M, Heide D, Shoshkes-Carmel M, Schmidt Arras D, Elgavish S, Nevo Y, Benyamini H, Tirnitz-Parker JEE, Sanchez A, Herrera B, Safadi R, Kaestner KH, Rose-John S, Roskams T, Heikenwalder M, Galun E. Rosenberg N, et al. Among authors: gefen m. J Hepatol. 2022 Dec;77(6):1631-1641. doi: 10.1016/j.jhep.2022.07.029. Epub 2022 Aug 18. J Hepatol. 2022. PMID: 35988690
The lncRNA H19-Derived MicroRNA-675 Promotes Liver Necroptosis by Targeting FADD.
Harari-Steinfeld R, Gefen M, Simerzin A, Zorde-Khvalevsky E, Rivkin M, Ella E, Friehmann T, Gerlic M, Zucman-Rossi J, Caruso S, Leveille M, Estall JL, Goldenberg DS, Giladi H, Galun E, Bromberg Z. Harari-Steinfeld R, et al. Among authors: gefen m. Cancers (Basel). 2021 Jan 22;13(3):411. doi: 10.3390/cancers13030411. Cancers (Basel). 2021. PMID: 33499244 Free PMC article.
Agonist of RORA Attenuates Nonalcoholic Fatty Liver Progression in Mice via Up-regulation of MicroRNA 122.
Chai C, Cox B, Yaish D, Gross D, Rosenberg N, Amblard F, Shemuelian Z, Gefen M, Korach A, Tirosh O, Lanton T, Link H, Tam J, Permyakova A, Ozhan G, Citrin J, Liao H, Tannous M, Hahn M, Axelrod J, Arretxe E, Alonso C, Martinez-Arranz I, Betés PO, Safadi R, Salhab A, Amer J, Tber Z, Mengshetti S, Giladi H, Schinazi RF, Galun E. Chai C, et al. Among authors: gefen m. Gastroenterology. 2020 Sep;159(3):999-1014.e9. doi: 10.1053/j.gastro.2020.05.056. Epub 2020 May 22. Gastroenterology. 2020. PMID: 32450149 Free PMC article.
Bioequivalence and Safety of Generic Glecaprevir/Pibrentasvir Compared to a Branded Product: A Randomized, Crossover Study in Healthy Volunteers.
Noskov S, Parulya O, Lutskova L, Arefeva A, Protsenko E, Banko V, Radaeva K, Matvienko I, Gefen M, Karnakova P, Knyazeva A, Komarov T, Archakova O, Shohin I. Noskov S, et al. Among authors: gefen m. Clin Pharmacol Drug Dev. 2024 Dec;13(12):1331-1338. doi: 10.1002/cpdd.1463. Epub 2024 Aug 14. Clin Pharmacol Drug Dev. 2024. PMID: 39140163 Clinical Trial.
Clinical Pharmacology of GP40321 (Insulin Glulisine Biosimilar): Pharmacokinetic and Pharmacodynamic Comparability in a Hyperinsulinemic-Euglycemic Clamp Procedure.
Koksharova E, Drai R, Noskov S, Dorotenko A, Protsenko E, Radaeva K, Arefeva A, Gefen M, Galstyan G, Makarenko I. Koksharova E, et al. Among authors: gefen m. Clin Pharmacol Drug Dev. 2024 Jul;13(7):828-836. doi: 10.1002/cpdd.1401. Epub 2024 Mar 21. Clin Pharmacol Drug Dev. 2024. PMID: 38515279 Clinical Trial.
A randomized, double-blind, comparative study of the pharmacodynamics and pharmacokinetics of GP40141 (romiplostim biosimilar) and reference romiplostim in healthy male volunteers.
Makarenko I, Dorotenko A, Noskov S, Banko V, Saparova V, Khokhlov A, Zoreeva E, Nedorubov A, Zinnatulina B, Gefen M, Drai R. Makarenko I, et al. Among authors: gefen m. Pharmacol Res Perspect. 2023 Oct;11(5):e01125. doi: 10.1002/prp2.1125. Pharmacol Res Perspect. 2023. PMID: 37740581 Free PMC article. Clinical Trial.