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Early macrophage response to obesity encompasses Interferon Regulatory Factor 5 regulated mitochondrial architecture remodelling.
Orliaguet L, Ejlalmanesh T, Humbert A, Ballaire R, Diedisheim M, Julla JB, Chokr D, Cuenco J, Michieletto J, Charbit J, Lindén D, Boucher J, Potier C, Hamimi A, Lemoine S, Blugeon C, Legoix P, Lameiras S, Baudrin LG, Baulande S, Soprani A, Castelli FA, Fenaille F, Riveline JP, Dalmas E, Rieusset J, Gautier JF, Venteclef N, Alzaid F. Orliaguet L, et al. Among authors: soprani a. Nat Commun. 2022 Aug 30;13(1):5089. doi: 10.1038/s41467-022-32813-z. Nat Commun. 2022. PMID: 36042203 Free PMC article.
Loss of the co-repressor GPS2 sensitizes macrophage activation upon metabolic stress induced by obesity and type 2 diabetes.
Fan R, Toubal A, Goñi S, Drareni K, Huang Z, Alzaid F, Ballaire R, Ancel P, Liang N, Damdimopoulos A, Hainault I, Soprani A, Aron-Wisnewsky J, Foufelle F, Lawrence T, Gautier JF, Venteclef N, Treuter E. Fan R, et al. Among authors: soprani a. Nat Med. 2016 Jul;22(7):780-91. doi: 10.1038/nm.4114. Epub 2016 Jun 6. Nat Med. 2016. PMID: 27270589
Functional and phenotypical analysis of IL-6-secreting CD4+ T cells in human adipose tissue.
de Jong AJ, Pollastro S, Kwekkeboom JC, Andersen SN, Dorjée AL, Bakker AM, Alzaid F, Soprani A, Nelissen RGHH, Mullers JB, Venteclef N, de Vries N, Kloppenburg M, Toes REM, Ioan-Facsinay A. de Jong AJ, et al. Among authors: soprani a. Eur J Immunol. 2018 Mar;48(3):471-481. doi: 10.1002/eji.201747037. Epub 2018 Jan 29. Eur J Immunol. 2018. PMID: 29283192 Free PMC article.
Loss of G protein pathway suppressor 2 in human adipocytes triggers lipid remodeling by upregulating ATP binding cassette subfamily G member 1.
Barilla S, Liang N, Mileti E, Ballaire R, Lhomme M, Ponnaiah M, Lemoine S, Soprani A, Gautier JF, Amri EZ, Le Goff W, Venteclef N, Treuter E. Barilla S, et al. Among authors: soprani a. Mol Metab. 2020 Dec;42:101066. doi: 10.1016/j.molmet.2020.101066. Epub 2020 Aug 13. Mol Metab. 2020. PMID: 32798719 Free PMC article.
ABCG1 orchestrates adipose tissue macrophage plasticity and insulin resistance in obesity by rewiring saturated fatty acid pools.
Dahik VD, Kc P, Materne C, Reydellet C, Lhomme M, Cruciani-Guglielmacci C, Denom J, Bun E, Ponnaiah M, Deknuydt F, Frisdal E, Hardy LM, Durand H, Guillas I, Lesnik P, Gudelj I, Lauc G, Guérin M, Kontush A, Soprani A, Magnan C, Diedisheim M, Bluteau O, Venteclef N, Le Goff W. Dahik VD, et al. Among authors: soprani a. Sci Transl Med. 2024 Dec 11;16(777):eadi6682. doi: 10.1126/scitranslmed.adi6682. Epub 2024 Dec 11. Sci Transl Med. 2024. PMID: 39661702
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