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Quantitative immunopeptidomics reveals a tumor stroma-specific target for T cell therapy.
Kim GB, Fritsche J, Bunk S, Mahr A, Unverdorben F, Tosh K, Kong H, Maldini CR, Lau C, Srivatsa S, Jiang S, Glover J, Dopkin D, Zhang CX, Schuster H, Kowalewski DJ, Goldfinger V, Ott M, Fuhrmann D, Baues M, Boesmueller H, Schraeder C, Schimmack G, Song C, Hoffgaard F, Roemer M, Tsou CC, Hofmann M, Treiber T, Hutt M, Alten L, Jaworski M, Alpert A, Missel S, Reinhardt C, Singh H, Schoor O, Walter S, Wagner C, Maurer D, Weinschenk T, Riley JL. Kim GB, et al. Among authors: riley jl. Sci Transl Med. 2022 Aug 31;14(660):eabo6135. doi: 10.1126/scitranslmed.abo6135. Epub 2022 Aug 31. Sci Transl Med. 2022. PMID: 36044599 Free PMC article.
Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells.
Scholler J, Brady TL, Binder-Scholl G, Hwang WT, Plesa G, Hege KM, Vogel AN, Kalos M, Riley JL, Deeks SG, Mitsuyasu RT, Bernstein WB, Aronson NE, Levine BL, Bushman FD, June CH. Scholler J, et al. Among authors: riley jl. Sci Transl Med. 2012 May 2;4(132):132ra53. doi: 10.1126/scitranslmed.3003761. Sci Transl Med. 2012. PMID: 22553251 Free PMC article. Clinical Trial.
Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5.
Maier DA, Brennan AL, Jiang S, Binder-Scholl GK, Lee G, Plesa G, Zheng Z, Cotte J, Carpenito C, Wood T, Spratt SK, Ando D, Gregory P, Holmes MC, Perez EE, Riley JL, Carroll RG, June CH, Levine BL. Maier DA, et al. Among authors: riley jl. Hum Gene Ther. 2013 Mar;24(3):245-58. doi: 10.1089/hum.2012.172. Epub 2013 Mar 6. Hum Gene Ther. 2013. PMID: 23360514 Free PMC article.
Strength of PD-1 signaling differentially affects T-cell effector functions.
Wei F, Zhong S, Ma Z, Kong H, Medvec A, Ahmed R, Freeman GJ, Krogsgaard M, Riley JL. Wei F, et al. Among authors: riley jl. Proc Natl Acad Sci U S A. 2013 Jul 2;110(27):E2480-9. doi: 10.1073/pnas.1305394110. Epub 2013 Apr 22. Proc Natl Acad Sci U S A. 2013. PMID: 23610399 Free PMC article.
Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.
Leibman RS, Richardson MW, Ellebrecht CT, Maldini CR, Glover JA, Secreto AJ, Kulikovskaya I, Lacey SF, Akkina SR, Yi Y, Shaheen F, Wang J, Dufendach KA, Holmes MC, Collman RG, Payne AS, Riley JL. Leibman RS, et al. Among authors: riley jl. PLoS Pathog. 2017 Oct 12;13(10):e1006613. doi: 10.1371/journal.ppat.1006613. eCollection 2017 Oct. PLoS Pathog. 2017. PMID: 29023549 Free PMC article.
374 results