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Allosteric cross-talk between the hydrophobic cleft and the BH4 domain of Bcl-2 in control of inositol 1,4,5-trisphosphate receptor activity.
Shapovalov G, Ritaine A, Essonghe NC, de Ridder I, Ivanova H, Karamanou S, Economou A, Bultynck G, Skryma R, Prevarskaya N. Shapovalov G, et al. Among authors: bultynck g. Explor Target Antitumor Ther. 2022;3(3):375-391. doi: 10.37349/etat.2022.00088. Epub 2022 Jun 28. Explor Target Antitumor Ther. 2022. PMID: 36045908 Free PMC article.
The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A. Bultynck G, et al. J Biol Chem. 2012 Jan 20;287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22128171 Free PMC article.
Profiling of the Bcl-2/Bcl-X(L)-binding sites on type 1 IP(3) receptor.
Monaco G, Beckers M, Ivanova H, Missiaen L, Parys JB, De Smedt H, Bultynck G. Monaco G, et al. Among authors: bultynck g. Biochem Biophys Res Commun. 2012 Nov 9;428(1):31-5. doi: 10.1016/j.bbrc.2012.10.002. Epub 2012 Oct 8. Biochem Biophys Res Commun. 2012. PMID: 23058917
One interaction site for Bcl-2 was proposed in the central part of the modulatory domain [Y.P. Rong, A.S. Aromolaran, G. Bultynck, F. Zhong, X. Li, K. McColl, S. Matsuyama, S. Herlitze, H.L. Roderick, M.D. Bootman, G.A. Mignery, J.B. Parys, H. De Smedt, C.W. …
One interaction site for Bcl-2 was proposed in the central part of the modulatory domain [Y.P. Rong, A.S. Aromolaran, G. Bultynck
256 results