Wack A - Search Results

1

Hypoxia inducible factors regulate infectious SARS-CoV-2, epithelial damage and respiratory symptoms in a hamster COVID-19 model.

Wing PAC, Prange-Barczynska M, Cross A, Crotta S, Orbegozo Rubio C, Cheng X, Harris JM, Zhuang X, Johnson RL, Ryan KA, Hall Y, Carroll MW, Issa F, Balfe P, Wack A, Bishop T, Salguero FJ, McKeating JA. Wing PAC, et al. Among authors: wack a. PLoS Pathog. 2022 Sep 6;18(9):e1010807. doi: 10.1371/journal.ppat.1010807. eCollection 2022 Sep. PLoS Pathog. 2022. PMID: 36067210 Free PMC article.

2

Type I and type III interferons drive redundant amplification loops to induce a transcriptional signature in influenza-infected airway epithelia.

Crotta S, Davidson S, Mahlakoiv T, Desmet CJ, Buckwalter MR, Albert ML, Staeheli P, Wack A. Crotta S, et al. Among authors: wack a. PLoS Pathog. 2013;9(11):e1003773. doi: 10.1371/journal.ppat.1003773. Epub 2013 Nov 21. PLoS Pathog. 2013. PMID: 24278020 Free PMC article.

3

The transcription factor E4BP4 is not required for extramedullary pathways of NK cell development.

Crotta S, Gkioka A, Male V, Duarte JH, Davidson S, Nisoli I, Brady HJ, Wack A. Crotta S, et al. Among authors: wack a. J Immunol. 2014 Mar 15;192(6):2677-88. doi: 10.4049/jimmunol.1302765. Epub 2014 Feb 17. J Immunol. 2014. PMID: 24534532 Free PMC article.

4

Pathogenic potential of interferon αβ in acute influenza infection.

Davidson S, Crotta S, McCabe TM, Wack A. Davidson S, et al. Among authors: wack a. Nat Commun. 2014 May 21;5:3864. doi: 10.1038/ncomms4864. Nat Commun. 2014. PMID: 24844667 Free PMC article.

5

TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection.

Ellis GT, Davidson S, Crotta S, Branzk N, Papayannopoulos V, Wack A. Ellis GT, et al. Among authors: wack a. EMBO Rep. 2015 Sep;16(9):1203-18. doi: 10.15252/embr.201540473. Epub 2015 Aug 11. EMBO Rep. 2015. PMID: 26265006 Free PMC article.

6

IFNλ is a potent anti-influenza therapeutic without the inflammatory side effects of IFNα treatment.

Davidson S, McCabe TM, Crotta S, Gad HH, Hessel EM, Beinke S, Hartmann R, Wack A. Davidson S, et al. Among authors: wack a. EMBO Mol Med. 2016 Sep 1;8(9):1099-112. doi: 10.15252/emmm.201606413. Print 2016 Sep. EMBO Mol Med. 2016. PMID: 27520969 Free PMC article.

7

The aryl hydrocarbon receptor controls cyclin O to promote epithelial multiciliogenesis.

Villa M, Crotta S, Dingwell KS, Hirst EM, Gialitakis M, Ahlfors H, Smith JC, Stockinger B, Wack A. Villa M, et al. Among authors: wack a. Nat Commun. 2016 Aug 24;7:12652. doi: 10.1038/ncomms12652. Nat Commun. 2016. PMID: 27554288 Free PMC article.

8

Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection.

Bradley KC, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, Fuchs SY, Staeheli P, Wack A. Bradley KC, et al. Among authors: wack a. Cell Rep. 2019 Jul 2;28(1):245-256.e4. doi: 10.1016/j.celrep.2019.05.105. Cell Rep. 2019. PMID: 31269444 Free article.

9

Influenza-induced monocyte-derived alveolar macrophages confer prolonged antibacterial protection.

Aegerter H, Kulikauskaite J, Crotta S, Patel H, Kelly G, Hessel EM, Mack M, Beinke S, Wack A. Aegerter H, et al. Among authors: wack a. Nat Immunol. 2020 Feb;21(2):145-157. doi: 10.1038/s41590-019-0568-x. Epub 2020 Jan 13. Nat Immunol. 2020. PMID: 31932810 Free PMC article.

10

Type I and III interferons disrupt lung epithelial repair during recovery from viral infection.

Major J, Crotta S, Llorian M, McCabe TM, Gad HH, Priestnall SL, Hartmann R, Wack A. Major J, et al. Among authors: wack a. Science. 2020 Aug 7;369(6504):712-717. doi: 10.1126/science.abc2061. Epub 2020 Jun 11. Science. 2020. PMID: 32527928 Free PMC article.

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