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Identification of trypsin-degrading commensals in the large intestine.
Li Y, Watanabe E, Kawashima Y, Plichta DR, Wang Z, Ujike M, Ang QY, Wu R, Furuichi M, Takeshita K, Yoshida K, Nishiyama K, Kearney SM, Suda W, Hattori M, Sasajima S, Matsunaga T, Zhang X, Watanabe K, Fujishiro J, Norman JM, Olle B, Matsuyama S, Namkoong H, Uwamino Y, Ishii M, Fukunaga K, Hasegawa N, Ohara O, Xavier RJ, Atarashi K, Honda K. Li Y, et al. Among authors: ohara o. Nature. 2022 Sep;609(7927):582-589. doi: 10.1038/s41586-022-05181-3. Epub 2022 Sep 7. Nature. 2022. PMID: 36071157 Free PMC article.
Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells.
Furusawa Y, Obata Y, Fukuda S, Endo TA, Nakato G, Takahashi D, Nakanishi Y, Uetake C, Kato K, Kato T, Takahashi M, Fukuda NN, Murakami S, Miyauchi E, Hino S, Atarashi K, Onawa S, Fujimura Y, Lockett T, Clarke JM, Topping DL, Tomita M, Hori S, Ohara O, Morita T, Koseki H, Kikuchi J, Honda K, Hase K, Ohno H. Furusawa Y, et al. Among authors: ohara o. Nature. 2013 Dec 19;504(7480):446-50. doi: 10.1038/nature12721. Epub 2013 Nov 13. Nature. 2013. PMID: 24226770
The epigenetic regulator Uhrf1 facilitates the proliferation and maturation of colonic regulatory T cells.
Obata Y, Furusawa Y, Endo TA, Sharif J, Takahashi D, Atarashi K, Nakayama M, Onawa S, Fujimura Y, Takahashi M, Ikawa T, Otsubo T, Kawamura YI, Dohi T, Tajima S, Masumoto H, Ohara O, Honda K, Hori S, Ohno H, Koseki H, Hase K. Obata Y, et al. Among authors: ohara o. Nat Immunol. 2014 Jun;15(6):571-9. doi: 10.1038/ni.2886. Epub 2014 Apr 28. Nat Immunol. 2014. PMID: 24777532
Generation of orthotopically functional salivary gland from embryonic stem cells.
Tanaka J, Ogawa M, Hojo H, Kawashima Y, Mabuchi Y, Hata K, Nakamura S, Yasuhara R, Takamatsu K, Irié T, Fukada T, Sakai T, Inoue T, Nishimura R, Ohara O, Saito I, Ohba S, Tsuji T, Mishima K. Tanaka J, et al. Among authors: ohara o. Nat Commun. 2018 Oct 11;9(1):4216. doi: 10.1038/s41467-018-06469-7. Nat Commun. 2018. PMID: 30310071 Free PMC article.
529 results