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Mcl-1 and Bcl-x(L) coordinately regulate megakaryocyte survival.
Debrincat MA, Josefsson EC, James C, Henley KJ, Ellis S, Lebois M, Betterman KL, Lane RM, Rogers KL, White MJ, Roberts AW, Harvey NL, Metcalf D, Kile BT. Debrincat MA, et al. Among authors: lebois m. Blood. 2012 Jun 14;119(24):5850-8. doi: 10.1182/blood-2011-12-398834. Epub 2012 Feb 28. Blood. 2012. PMID: 22374700 Free article.
Regulation of platelet lifespan by apoptosis.
Lebois M, Josefsson EC. Lebois M, et al. Platelets. 2016 Sep;27(6):497-504. doi: 10.3109/09537104.2016.1161739. Epub 2016 Apr 21. Platelets. 2016. PMID: 27100842 Free article. Review.
Altered B-lymphopoiesis in mice with deregulated thrombopoietin signaling.
Au AE, Lebois M, Sim SA, Cannon P, Corbin J, Gangatirkar P, Hyland CD, Moujalled D, Rutgersson A, Yassinson F, Kile BT, Mason KD, Ng AP, Alexander WS, Josefsson EC. Au AE, et al. Among authors: lebois m. Sci Rep. 2017 Nov 2;7(1):14953. doi: 10.1038/s41598-017-15023-2. Sci Rep. 2017. PMID: 29097774 Free PMC article.
Intrinsic apoptosis circumvents the functional decline of circulating platelets but does not cause the storage lesion.
Pleines I, Lebois M, Gangatirkar P, Au AE, Lane RM, Henley KJ, Kauppi M, Corbin J, Cannon P, Bernardini J, Alwis I, Jarman KE, Ellis S, Metcalf D, Jackson SP, Schoenwaelder SM, Kile BT, Josefsson EC. Pleines I, et al. Among authors: lebois m. Blood. 2018 Jul 12;132(2):197-209. doi: 10.1182/blood-2017-11-816355. Epub 2018 May 21. Blood. 2018. PMID: 29784641 Free article.
BCL-2 is dispensable for thrombopoiesis and platelet survival.
Debrincat MA, Pleines I, Lebois M, Lane RM, Holmes ML, Corbin J, Vandenberg CJ, Alexander WS, Ng AP, Strasser A, Bouillet P, Sola-Visner M, Kile BT, Josefsson EC. Debrincat MA, et al. Among authors: lebois m. Cell Death Dis. 2015 Apr 16;6(4):e1721. doi: 10.1038/cddis.2015.97. Cell Death Dis. 2015. PMID: 25880088 Free PMC article.
20 results