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Cold shock domain-containing protein E1 is a posttranscriptional regulator of the LDL receptor.
Smith GA, Padmanabhan A, Lau BH, Pampana A, Li L, Lee CY, Pelonero A, Nishino T, Sadagopan N, Xia VQ, Jain R, Natarajan P, Wu RS, Black BL, Srivastava D, Shokat KM, Chorba JS. Smith GA, et al. Among authors: lee cy. Sci Transl Med. 2022 Sep 14;14(662):eabj8670. doi: 10.1126/scitranslmed.abj8670. Epub 2022 Sep 14. Sci Transl Med. 2022. PMID: 36103516 Free PMC article.
A transcriptional switch governs fibroblast activation in heart disease.
Alexanian M, Przytycki PF, Micheletti R, Padmanabhan A, Ye L, Travers JG, Gonzalez-Teran B, Silva AC, Duan Q, Ranade SS, Felix F, Linares-Saldana R, Li L, Lee CY, Sadagopan N, Pelonero A, Huang Y, Andreoletti G, Jain R, McKinsey TA, Rosenfeld MG, Gifford CA, Pollard KS, Haldar SM, Srivastava D. Alexanian M, et al. Among authors: lee cy. Nature. 2021 Jul;595(7867):438-443. doi: 10.1038/s41586-021-03674-1. Epub 2021 Jun 23. Nature. 2021. PMID: 34163071 Free PMC article.
Transcription factor protein interactomes reveal genetic determinants in heart disease.
Gonzalez-Teran B, Pittman M, Felix F, Thomas R, Richmond-Buccola D, Hüttenhain R, Choudhary K, Moroni E, Costa MW, Huang Y, Padmanabhan A, Alexanian M, Lee CY, Maven BEJ, Samse-Knapp K, Morton SU, McGregor M, Gifford CA, Seidman JG, Seidman CE, Gelb BD, Colombo G, Conklin BR, Black BL, Bruneau BG, Krogan NJ, Pollard KS, Srivastava D. Gonzalez-Teran B, et al. Among authors: lee cy. Cell. 2022 Mar 3;185(5):794-814.e30. doi: 10.1016/j.cell.2022.01.021. Epub 2022 Feb 18. Cell. 2022. PMID: 35182466 Free PMC article.
Chromatin Remodeling Drives Immune-Fibroblast Crosstalk in Heart Failure Pathogenesis.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Lee CY, Sadagopan N, Huang Y, Pelonero A, Auclair K, Zhu A, Teran BG, Flanigan W, Kim CK, Lumbao-Conradson K, Costa M, Jain R, Charo I, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Among authors: lee cy. bioRxiv [Preprint]. 2023 Jan 7:2023.01.06.522937. doi: 10.1101/2023.01.06.522937. bioRxiv. 2023. PMID: 36711864 Free PMC article. Preprint.
A genome-wide CRISPR screen identifies BRD4 as a regulator of cardiomyocyte differentiation.
Padmanabhan A, de Soysa TY, Pelonero A, Sapp V, Shah PP, Wang Q, Li L, Lee CY, Sadagopan N, Nishino T, Ye L, Yang R, Karnay A, Poleshko A, Bolar N, Linares-Saldana R, Ranade SS, Alexanian M, Morton SU, Jain M, Haldar SM, Srivastava D, Jain R. Padmanabhan A, et al. Among authors: lee cy. Nat Cardiovasc Res. 2024 Mar;3(3):317-331. doi: 10.1038/s44161-024-00431-1. Epub 2024 Feb 23. Nat Cardiovasc Res. 2024. PMID: 39196112 Free PMC article.
Chromatin remodelling drives immune cell-fibroblast communication in heart failure.
Alexanian M, Padmanabhan A, Nishino T, Travers JG, Ye L, Pelonero A, Lee CY, Sadagopan N, Huang Y, Auclair K, Zhu A, An Y, Ekstrand CA, Martinez C, Teran BG, Flanigan WR, Kim CK, Lumbao-Conradson K, Gardner Z, Li L, Costa MW, Jain R, Charo I, Combes AJ, Haldar SM, Pollard KS, Vagnozzi RJ, McKinsey TA, Przytycki PF, Srivastava D. Alexanian M, et al. Among authors: lee cy. Nature. 2024 Nov;635(8038):434-443. doi: 10.1038/s41586-024-08085-6. Epub 2024 Oct 23. Nature. 2024. PMID: 39443808
A conserved pilin from uncultured gut bacterial clade TANB77 enhances cancer immunotherapy.
Kim CY, Park DJ, Ahn BC, Baek S, Hong MH, Nguyen LT, Hwang SH, Kim N, Podlesny D, Orakov A, Schudoma C, Robbani SM, Shim HS, Yoon HI, Lee CY, Park SY, Yong D, Han M, Bork P, Kim BC, Ha SJ, Kim HR, Lee I. Kim CY, et al. Among authors: lee cy. Nat Commun. 2024 Dec 27;15(1):10726. doi: 10.1038/s41467-024-55388-3. Nat Commun. 2024. PMID: 39730328 Free article.
Current Approaches to Optimize Donor Heart for Transplantation.
Alam AH, Lee CY, Kanwar MK, Moayedi Y, Bernhardt AM, Takeda K, Pham DT, Salerno C, Zuckermann A, D'Alessandro D, Pretorius VG, Louca JO, Large S, Bowles DE, Silvestry SC, Moazami N. Alam AH, et al. Among authors: lee cy. J Heart Lung Transplant. 2024 Dec 25:S1053-2498(24)02012-6. doi: 10.1016/j.healun.2024.12.001. Online ahead of print. J Heart Lung Transplant. 2024. PMID: 39730081 Review.
4,618 results