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RNA-sequencing and mass-spectrometry proteomic time-series analysis of T-cell differentiation identified multiple splice variants models that predicted validated protein biomarkers in inflammatory diseases.
Magnusson R, Rundquist O, Kim MJ, Hellberg S, Na CH, Benson M, Gomez-Cabrero D, Kockum I, Tegnér JN, Piehl F, Jagodic M, Mellergård J, Altafini C, Ernerudh J, Jenmalm MC, Nestor CE, Kim MS, Gustafsson M. Magnusson R, et al. Among authors: altafini c. Front Mol Biosci. 2022 Aug 29;9:916128. doi: 10.3389/fmolb.2022.916128. eCollection 2022. Front Mol Biosci. 2022. PMID: 36106020 Free PMC article.
Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis.
Åkesson J, Hojjati S, Hellberg S, Raffetseder J, Khademi M, Rynkowski R, Kockum I, Altafini C, Lubovac-Pilav Z, Mellergård J, Jenmalm MC, Piehl F, Olsson T, Ernerudh J, Gustafsson M. Åkesson J, et al. Among authors: altafini c. Nat Commun. 2023 Oct 30;14(1):6903. doi: 10.1038/s41467-023-42682-9. Nat Commun. 2023. PMID: 37903821 Free PMC article.
A system-level approach for deciphering the transcriptional response to prion infection.
Zampieri M, Legname G, Segrè D, Altafini C. Zampieri M, et al. Among authors: altafini c. Bioinformatics. 2011 Dec 15;27(24):3407-14. doi: 10.1093/bioinformatics/btr580. Epub 2011 Oct 20. Bioinformatics. 2011. PMID: 22016408
As a first result of our inference, we have been able to predict known targets of prions (i.e. PrP(C)) and to unveil the potential role of previously unsuspected genes. CONTACT: altafini@sissa.it SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinfo …
As a first result of our inference, we have been able to predict known targets of prions (i.e. PrP(C)) and to unveil the potential ro …
42 results